Publications by authors named "Sin-Guang Chen"
Article Synopsis
- Ulcerative colitis is an inflammatory bowel disease with limited treatments, and recent studies suggest tricin, a compound from rice bran, could help by reducing inflammation and its related effects.
- The study tested tricin's effects on specific immune cells and its efficacy in a mouse model of acute colitis, comparing it with the standard drug sulfasalazine.
- Results indicated that tricin significantly decreased inflammation and helped restore gut health in mice, suggesting it could be a promising treatment for ulcerative colitis.
The common occurrence of cardiovascular diseases and the lack of proper autologous tissues prompt and promote the pressing development of tissue-engineered vascular grafts (TEVGs). Current progress on scaffold production, genetically modified cells, and use of nanotechnology-based monitoring has considerably improved the long-term patency of engineered tissue grafts. However, challenges abound in the autologous materials and manipulation of genes and cells for tissue engineering.
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- * While RT-PCR is the primary method for diagnosing COVID-19, it has a concerning false-negative rate, prompting the use of radiographic tools like CT scans and chest X-rays for better initial screening and diagnosis.
- * The review will address the difficulties in diagnostics, including shortages of sampling kits and delays in PCR testing, and explore future possibilities for improving radiographic methods in the diagnosis of COVID-19 to save lives during the ongoing crisis.
Myopia is the commonest eye disorder in the world. High myopes are predisposed to ocular pathologies. The vasoactive intestinal peptide receptor 2 (VIPR2) gene was identified as a myopia susceptibility locus by our group and another group.
View Article and Find Full Text PDFBackground: Epilepsy is a neurological disorder characterized by abnormal neuron discharge, and one-third of epilepsy patients suffer from drug-resistant epilepsy (DRE). The current management for DRE includes epileptogenic lesion resection, disconnection, and neuromodulation. Neuromodulation is achieved through invasive electrical stimulus including deep brain stimulation, vagus nerve stimulation, or responsive neurostimulation (RNS).
View Article and Find Full Text PDFEnterovirus 71 (EV71) infection is endemic in the Asia-Pacific region. No specific antiviral drug has been available to treat EV71 infection. Melissa officinalis (MO) is a medicinal plant with long history of usage in the European and Middle East.
View Article and Find Full Text PDFNo effective drug is currently available for treatment of enterovirus 71 (EV71) infection. Schizonepeta tenuifolia Briq. (ST) has been used as a herbal constituent of traditional Chinese medicine.
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