Publications by authors named "Simsek O"

Application of melatonin and lipopeptides (LPs) derived from Bacillus strains is considered an efficient strategy to control plant diseases at both pre and postharvest stages. However, the combined application of melatonin and LPs has not been studied yet. Therefore, the present study presents the synergistic effect of melatonin and LPs produced by Bacillus atrophaeus strain MCM61 against gray mold disease and its impact on quality parameters and vase life of cut roses.

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Obtaining virus-free plants is a crucial step in disease management that enables reliable and profitable fruit farming. The present study applied various in vitro virus elimination protocols, including apical shoot culture, chemotherapy, thermotherapy, cryotherapy, and their combination, to eliminate black mulberry Idaeovirus (BMIV) from sour black mulberry. First, a shoot tip (0.

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Article Synopsis
  • * The study analyzed 150 patients who underwent laparoscopic appendectomy to compare the effectiveness and safety of three stump closure methods: endoloop, Hem-o-lok clips, and endostaplers.
  • * Results showed that 96% of patients experienced no major complications, while the remaining 4% had issues, indicating that all three closure methods can be effective, though more research is needed on the best approach.
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Background: Acute appendicitis is one of the most common surgical emergencies. With antibiotic-first treatment strategies gaining importance, the risk of an appendiceal tumor as an incidental finding or as the cause of appendicitis presents an obstacle to a conservative approach. Neuroendocrine tumors, the most frequent type of appendiceal tumors, are difficult to diagnose preopera-tively due to their small size.

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Non-alcoholic fatty liver disease (NAFLD) is a growing global health concern closely linked to metabolic disorders, including obesity, insulin resistance, and dyslipidemia. Emerging evidence suggests that the gut-liver axis plays a critical role in the pathogenesis of NAFLD, with recent research highlighting the influence of gut microbiota, including fungal species such as Saccharomyces boulardii (). This study aimed to evaluate the effects of on lipid metabolism and oxidative stress in a rat model of fructose-induced NAFLD.

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Article Synopsis
  • * Methods: The study examined how different myrtle genotypes perform under drought by using tissue culture and various machine learning models to predict growth efficiency based on PEG treatments.
  • * Results: Black-fruited myrtle genotypes showed better growth rates under drought stress than white-fruited ones; machine learning effectively predicted their performance, emphasizing the need for selecting drought-tolerant plants for better cultivation practices.
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Background: Acute appendicitis is a common cause of acute abdominal pain necessitating surgical intervention. While the traditional treatment has been urgent appendectomy, recent studies suggest that an antibiotics-first approach can be safe for uncomplicated cases. Classifying appendicitis into uncomplicated and complicated categories is crucial for guiding treatment decisions and predicting patient outcomes.

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Evaluating lung "volumes" when interpreting pediatric chest radiographs is useful for supporting the diagnosis of lung pathology in children. Lung volumes can be estimated using semi-objective criteria such as anterior rib counting. Estimating lung volumes is one advantage plain radiographs have over other imaging modalities such as ultrasound or even cross-sectional imaging (Computed Tomography and Magnetic Resonance Imaging, where volumes can be calculated, but remain difficult to quickly be appreciated subjectively or semi-objectively in clinical practice).

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Background: Soil contamination with heavy metals poses a significant threat to plant health and human well-being. This study explores the potential of nano silica as a solution for mitigating heavy metal uptake in Calendula officinalis.

Results: Greenhouse experiments demonstrated, 1000 mg•kg nano silica caused a 6% increase in soil pH compared to the control treatment.

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Background And Purpose: Hemangioblastoma is a rare vascular tumor that occurs within the central nervous system in children. Differentiating hemangioblastoma from other posterior fossa tumors can be challenging on imaging, and preoperative diagnosis can change the neurosurgical approach. We hypothesize that a "lightbulb sign" on the arterial spin-labeling (ASL) sequence (diffuse homogeneous intense hyperperfusion within the solid component of the tumor) will provide additional imaging finding to differentiate hemangioblastoma from other posterior fossa tumors.

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Aim: Advanced neuroimaging strategies may provide new insights into the underlying mechanisms of trigeminal neuralgia (TN). The objective of this study is to measure central pain centers in patients with long-standing trigeminal neuralgia and compare them to those of normal individuals. The findings of this study could improve the understanding of central region changes related to pain and improve the diagnosis and management of chronic trigeminal pain.

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Board, card or video games have been played by virtually every individual in the world. Games are popular because they are intuitive and fun. These distinctive qualities of games also make them ideal for studying the mind.

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This study investigates the influence of cadmium (Cd) stress on the micropropagation of Goji Berry (Lycium barbarum L.) across three distinct genotypes (ERU, NQ1, NQ7), employing an array of machine learning (ML) algorithms, including Multilayer Perceptron (MLP), Support Vector Machines (SVM), Random Forest (RF), Gaussian Process (GP), and Extreme Gradient Boosting (XGBoost). The primary motivation is to elucidate genotype-specific responses to Cd stress, which poses significant challenges to agricultural productivity and food safety due to its toxicity.

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Purpose: The traditional imaging findings reported in Sturge-Weber syndrome (SWS) include endpoints of cortical injury-cortical atrophy and cortical calcifications-but also what has been termed a "leptomeningeal angiomatosis," the latter recognized and reported as a leptomeningeal enhancement on magnetic resonance imaging (MRI). The objective of this study is to demonstrate through neuropathological correlation that the "leptomeningeal angiomatosis" in patients with Sturge-Weber syndrome (SWS), represents a re-opened primitive venous network in the subarachnoid space that likely acts as an alternative venous drainage pathway, seen separately to abnormal pial enhancement.

Materials And Methods: Retrospective review of MR imaging and surgical pathology of patients that underwent surgery for epilepsy at a tertiary, children's hospital.

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Background: This study evaluated the use of metformin or pioglitazone in preventing or reducing the development of post-operative intra-abdominal adhesion (PIAA) by employing histopathological, immunohistochemical, and biochemical analyses in an experimental adhesion model.

Methods: Fifty Wistar-Albino rats were divided into five groups: Group I (Control), Group II (Sham Treatment), Group III (Hy-aluronic Acid), Group IV (Metformin), and Group V (Pioglitazone). Adhesions were induced in the experimental groups, except for the sham group, using the scraping method.

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Background: Hepatic ischemia/reperfusion (I/R) injury is a significant clinical condition that can arise during liver resections, trauma, and shock. Geraniol, an isoterpene molecule commonly found in nature, possesses antioxidant and hepatoprotective properties. This study investigates the impact of geraniol on hepatic damage by inducing experimental liver I/R injury in rats.

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The division and evaluation of data series used in monitoring drought into different time intervals is a practical approach to detecting the spatial and temporal extent of drought spread. This study aimed to determine meteorological drought's spatial and temporal distribution using overlapping and consecutive periods and cycles of the standardized precipitation index (SPI) time series in the Mediterranean region, Turkey. In the scope of the research, SPI values for the SPI12, SPI6 (1), and SPI6 (2) seasons were calculated for consecutive and overlapping hydrological years (1978-1998/21 years, 1978-2008/31 years, and 1978-2018/41 years) at 28 meteorological stations.

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Background: The natural population of Colchicum figlalii (Varol) Parolly and Eren grows in a narrow area of serpentine rock clearings at an altitude of 1900-2100 m in Southwestern Anatolia (Sandras Mountain, Mugla, Turkey). The species is regarded as endangered according to the IUCN Red List Categories.

Objective: To develop an optimum procedure for in vitro propagation and cryopreservation of germplasm of this rare endemic.

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Rationale And Objectives: Artificial intelligence (AI) technologies are rapidly evolving and offering new advances almost on a day-by-day basis, including various tools for manuscript generation and modification. On the other hand, these potentially time- and effort-saving solutions come with potential bias, factual error, and plagiarism risks. Some journals have started to update their author guidelines in reference to AI-generated or AI-assisted manuscripts.

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Background And Purpose: In fetuses with lateral ventriculomegaly and normal posterior fossa cerebrospinal spaces, third ventricle distention is a compelling clue that supports a diagnosis of aqueductal stenosis. However, this association assumes normal ventricular anatomy. Structural constraints can impair pressure-induced compliance.

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Background: Mammography, used for breast cancer (BC) screening, has limitations such as decreased sensitivity in dense breasts. Currently used tumor markers are insufficient in diagnosing breast cancer. In this study, we aimed to investigate the relationship between serum levels of synaptophysin-like protein 1 (SYPL1) and BC and compare SYPL1 with other blood tumor markers.

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Objectives: Biliary cysts are biliary duct dilatations, with 20% of the cysts being diagnosed in adulthood. Abdominal pain, jaundice and palpable abdominal mass are defined as the classical triad. However, nausea, vomiting, fever, itching and weight loss are frequent complaints.

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Background: The objective was to provide comprehensive preoperative information on both the aneurysm orientation and the side and method of surgical approach for optimal preoperative information and safe clipping using 3D imaging modalities. This was achieved by making an objective risk assessment on the surgical side/method and evaluating its effectiveness with internal validation.

Materials And Methods: Radiologic data of 61 ACoA aneurysm patients between 2012 and 2020 were retrospectively analyzed.

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