Publications by authors named "Simran Khemlani Ramchand"
Article Synopsis
- Diabetes can be a risk factor for cancer, but there is limited research on how post-transplant diabetes mellitus (PTDM) influences cancer risk after organ transplants.
- In a study of Spanish patients without diabetes before transplant, researchers found that PTDM did not generally increase cancer risk, but indicated a significant association with renal cell cancer (RCC).
- The study suggests that patients with PTDM should be monitored closely for RCC due to their higher risk compared to those without PTDM.
Post-transplant diabetes mellitus (PTDM) is a frequent and relevant complication after renal transplantation: it affects 20-30% of renal transplant recipients and increases the risk for cardiovascular and infectious events. Thus, understanding pathogenesis of PTDM would help limiting its consequences. In this review, we analyse novel aspects of PTDM, based on studies of the last decade, such as the clinical evolution of PTDM, early and late, the reversibility rate, diagnostic criteria, risk factors, including pre-transplant metabolic syndrome and insulin resistance (IR) and the interaction between these factors and immunosuppressive medications.
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