[Latent tuberculosis infection in children in Bangui: about 524 cases exposed at home to index cases of positive microscopy pulmonary tuberculosis].

Introduction: in endemic areas, despite BCG vaccination, the risk of developing tuberculosis (TB) in young children is high after exposure to adults with tuberculosis. The purpose of this study is to reduce the risk of active tuberculosis in children experiencing household exposure to adult index cases.

Methods: we conducted a cross-sectional multi-site study (April 2016- January 2019) of children aged 0 to 59 months experiencing household exposure to index cases.

Fatal Outcome in a Hepatitis E Virus/Human Immunodeficiency Virus Co-Infected Malnourished Child in the Central African Republic.

Hepatitis E virus (HEV) infection is responsible for major endemic outbreaks in developing countries. Human immunodeficiency virus (HIV) and HEV are widespread in the Central African Republic. We report the first documented case of an HEV infection in a 36-month-old child already suffering from HIV and severe acute malnutrition (SAM).