The Revised Reflux Symptom Index (R-RSI): Development, Internal and External Validation Study.

Introduction: This study proposes a revised version of the Reflux Symptom Index (R-RSI), a seventeen-item questionnaire that was revised to increase the suspicion of laryngopharyngeal reflux disease (LPRD).

Methods: Internal validation involved 213 participants, comprising 160 subjects without a previous LPRD diagnosis and 53 subjects with a self-reported previous diagnosis of LPRD with or without gastroesophageal reflux disease (GERD). Test-retest reliability and internal consistency were calculated.

Wettable sulphur application for Halyomorpha halys (Stål) (Hemiptera: Pentatomidae) management: laboratory and semi-field experiments.

Background: The brown marmorated stink bug, Halyomorpha halys (Stål) (Hemiptera: Pentatomidae), is a significant threat to crop production. Alternatives to synthetic pesticides are needed for its management. Here we investigated the effect of sulphur on H.

Optofluidic Flow Cytometer with In-Plane Spherical Mirror for Signal Enhancement.

Statistical analysis of the properties of single microparticles, such as cells, bacteria or plastic slivers, has attracted increasing interest in recent years. In this regard, field flow cytometry is considered the gold standard technique, but commercially available instruments are bulky, expensive, and not suitable for use in point-of-care (PoC) testing. Microfluidic flow cytometers, on the other hand, are small, cheap and can be used for on-site analyses.

Optical control of light polarization in heliconical cholesteric liquid crystals.

We show here that light polarization of a beam propagating through a heliconical cholesteric cell can be controlled by tuning the Bragg resonance of the structure. We demonstrate that this control is achieved by varying either the low-frequency electric field or the intensity of a pump beam impinging on the sample. The study confirms the recently reported phenomenon of optical tuning of the heliconical cholesterics and opens the door for the development of simple and efficient polarization modulators controlled electrically or optically.

Dysphagia in Parkinson's disease: Pharyngeal manometry and fiberoptic endoscopic evaluation.

Objective: Dysphagia is a common symptom in Parkinson's disease (PD) and it represents a negative prognostic factor because of its complications. This study is to evaluate pharyngeal dysphagia for boluses of various consistencies with Fiberoptic Endoscopic Evaluation of Swallowing (FEES) and Pharyngeal High-Resolution Manometry (PHRM) in a group of PD patients, making a comparison between the information provided by the two exams.

Methods: Group of 20 patients affected by PD was selected and initially subjected to a qualitative evaluation of the swallowing performing FEES.

Complications during Fiberoptic Endoscopic Evaluation of Swallowing in 5,680 Examinations.

Objective: To evaluate retrospectively the incidence of complications during fiberoptic endoscopic evaluation of swallowing (FEES) in 5,680 examinations.

Patients And Methods: 5,680 patients were evaluated at the Department of Otorhinolaryngology, Audiology and Phoniatrics of Pisa University Hospital between January 2014 and December 2018, involving both inpatients and outpatients. Most common comorbidities included neurological pathologies such as stroke (11.

Photo-Responsivity Improvement of Photo-Mobile Polymers Actuators Based on a Novel LCs/Azobenzene Copolymer and ZnO Nanoparticles Network.

The efficiency of photomobile polymers (PMP) in the conversion of light into mechanical work plays a fundamental role in achieving cutting-edge innovation in the development of novel applications ranging from energy harvesting to sensor approaches. Because of their photochromic properties, azobenzene monomers have been shown to be an efficient material for the preparation of PMPs with appropriate photoresponsivity. Upon integration of the azobenzene molecules as moieties into a polymer, they act as an engine, allowing fast movements of up to 50 Hz.

Nonlinear optical propagation near the Bragg resonance in heliconical cholesteric liquid crystals.

We show here that the light-induced tuning of the Bragg reflection recently demonstrated in heliconical cholesterics opens new perspectives to nonlinear optical propagation in liquid crystals. We highlight that, by properly adjusting the static electric field that stabilizes the heliconical structure, a dramatic change of the refractive index of the circularly polarized resonant mode can be achieved. Additionally, a stop band for a definite range of light intensity is obtained that can be tuned in order to get the conditions of self-induced transparency.

Reflux Symptom Index (RSI) and Singing Voice Handicap Index (SVHI) in Singing Students: A Pilot Study.

Objective: To correlate, RSI with SVHI, in a group of singing students, by means of a specific anamnestic questionnaire which analyzes the physical, social, emotional, and economic impacts of voice problems on their lives. This study is a cross-sectional single-center observational study.

Methods: Forty-two modern singing students (26F/16M; average age: 24.

Light-actuated contactless macro motors exploiting Bénard-Marangoni convection.

Near-infrared light is commonly used to move small objects floating on water by exploiting the Bénard-Marangoni convection. This is because infrared light is absorbed well by water and the induced thermal gradients are responsible for the objects' motion. However, visible light was recently used to move macroscopic objects on the free liquid surfaces.

Optofluidic platform using liquid crystals in lithium niobate microchannel.

We demonstrate the all optical control of the molecular orientation of nematic liquid crystals confined in microfluidic channels engraved in lithium niobate. Microchannels are obtained by a novel approach based on femtosecond pulse laser micromachining carried on in controlled atmosphere. The combined effect of photovoltaic and pyroelectric fields generated by light in lithium niobate crystals on the liquid crystal orientation, is reported for the first time.

Giant optical nonlinearity in DNA lyotropic liquid crystals.

We report the experimental evidence of nonlinear optical response in DNA lyotropic nematic liquid crystals. Pump-probe experiments indicate that the non-linearity is remarkably large. Quantitative assessment of the non-linear optical coefficient by transient optical grating demonstrates that the response is of the same order of the well-known Giant Optical Nonlinearity (GON) of thermotropic nematics.

Decision-Making on Withholding or Withdrawing Life Support in the ICU: A Worldwide Perspective.

Background: Many critically ill patients who die will do so after a decision has been made to withhold/withdraw life-sustaining therapy. The objective of this study was to document the characteristics of ICU patients with a decision to withhold/withdraw life-sustaining treatment, including the types of supportive treatments used, patterns of organ dysfunction, and international differences, including gross national income (GNI).

Methods: In this observational cohort study conducted in 730 ICUs in 84 countries, all adult patients admitted between May 8, 2012, and May 18, 2012 (except admissions for routine postoperative surveillance), were included.

Low threshold Fabry-Perot optofluidic resonator fabricated by femtosecond laser micromachining.

We report the realization and characterization of an optofluidic microlaser based on a Fabry-Perot resonator fabricated by exploiting two direct writing fabrication techniques: the femtosecond laser micromachining and the inkjet printing technology. In this way a standard Fabry-Perot cavity has been integrated into an optofluidic chip. When using rhodamine 6G dissolved in ethanol at concentration of 5∙10 mol/l, laser emission was detected at a threshold energy density of 1.

Structured beam diffraction.

We report on the observation of a modulated pattern induced by a single laser beam in a polymeric film. In spite of the simple geometrical configuration, the analysis of the far field diffraction pattern allows a sensitive retrieving of the wavelength of the recording beam and of its incidence angle, pointing out the high information content of the recorded spot. A theoretical model is presented which satisfactorily explains the observed behavior.

Light controlled phase shifter for optofluidics.

We report the light-induced control of optical phase shift by a liquid crystal cell made with LiNbO3:Fe crystals as substrates. We show that a phase shift of a few πs can be easily reached for two orthogonal polarizations due to liquid crystal reorientation driven by the photovoltaic electric field originated in the substrates. This effect is exploited to get all-optical switching with a contrast of about 80%, by 2 s pump pulse.

Sepsis due to pyonephrosis: an adult with pelvic-ureteric junction obstruction (PUJO) in a duplex kidney.

We present the case of a 75-year-old woman with sepsis. She was evaluated with bedside ultrasound with a diagnosis of pyonephrosis, and subsequently underwent a TC scan that showed a pelvic-ureteric junction obstruction (PUJO) in a duplicated renal system. PUJO associated with duplex kidney, while relatively frequent in children, is a rare condition in adults, and may lead to severe complications as in this case.

Optical nonlinearity in the nematic phase of bent-core mesogens.

Nonlinear optical response of the cybotactic nematic phase of a bent-core mesogen has been investigated for the first time through self-phase modulation induced by a Gaussian beam. The material exhibits a high nonlinear response achieving a nonlinear index n(2)≈5×10(-5)  cm(2)/W and an unconventional behavior characterized by two different regimes. While the high-intensity regime can be easily explained in terms of a thermal indexing effect, the low-intensity regime is metastable and characterized by an unusual dependence on the irradiation energy.

Role of space charges on light-induced effects in nematic liquid crystals doped by methyl red.

We show that both the extraordinarily large nonlinear response and the light-induced permanent reorientation in liquid crystals doped by the azo dye methyl red originates from the same phenomenon of modification of the charge density on the irradiated surface. The demonstration is done by applying ac voltage to the samples, showing that in this case no permanent anchoring is possible. The measurements confirm the role of photoisomerization that gives a transient contribution to the actual reorientation process only in the high dose regime.

Lung ultrasound during hemodialysis: the role in the assessment of volume status.

Objective: Fluid balance is important in patients undergoing hemodialysis. "Dry" weight is usually estimated clinically, and also, bioimpedance is considered reliable. Ultrasonography of inferior vena cava (IVC) estimates central venous pressure, and lung ultrasound evaluates extravascular (counting B-lines artifact) lung water.

First-order optical Freedericksz transition in a dye-doped nematic liquid crystal.

A first-order optical Freedericksz transition in a nematic liquid crystal doped by a small quantity of a dichroic dye with negative dichroism is observed. The initial homeotropic state corresponds to maximum absorption for the linearly polarized incident beam, while reorientation reduces absorption increasing the optical torque: this process produces the positive feedback leading to the observed bistable behavior.