Publications by authors named "Simonetta Crisa"
Article Synopsis
- Clinical evaluations of patients with SCN5A or new SCN10A variants indicated that their clinical features, like heart-related history and ECG patterns, are similar.
- Future research is needed to investigate the implications of specific SCN10A variants in relation to the Brugada syndrome.
In this case series, we report for the first time a family in which the inherited nonsense mutation [c. 3946C > T (p.Arg1316*)] in the gene segregates in association with Brugada syndrome (BrS).
View Article and Find Full Text PDFElectrical Substrate Elimination in 135 Consecutive Patients With Brugada Syndrome.
Circ Arrhythm Electrophysiol
May 2017
Background: There is emerging evidence that localization and elimination of abnormal electric activity in the epicardial right ventricular outflow tract may be beneficial in patients with Brugada syndrome.
Methods And Results: A total of 135 symptomatic Brugada syndrome patients having implantable cardiac defibrillator were enrolled: 63 (group 1) having documented ventricular tachycardia (VT)/ventricular fibrillation (VF) and Brugada syndrome-related symptoms, and 72 (group 2) having inducible VT/VF without ECG documentation at the time of symptoms. About 27 patients of group 1 experienced multiple implantable cardiac defibrillator shocks for recurrent VT/VF episodes.
Background: Nonirrigated magnetic ablation may result in potential char, ineffective lesions, and longer procedure times.
Objective: This study sought to report the safety and long-term efficacy of irrigated-tip magnetic ablation of atrial fibrillation (AF).
Methods: Catheter ablation was remotely performed using a new irrigated-tip magnetic catheter (ThermoCool NaviStar-RMT, Biosense Webster, Diamond Bar, CA) in 130 consecutive patients (mean age 59.
Background: Pulmonary vein isolation (PVI) is one of the common endpoints of all atrial fibrillation (AF) ablation procedures and is most often validated using a preshaped circular catheter. However, three-dimensional (3D) electroanatomical systems used for anatomy reconstruction and to guide coalescent delivery of ablation lesions avoid the use of multiple transeptal punctures and multiple catheters in the left atrium.
Objective: To assess correspondence in PVI validation between a 3D electroanatomical system and a Lasso catheter.