Solidagenone from Meyen Protects against Acute Peritonitis and Lipopolysaccharide-Induced Shock by Regulating NF-κB Signaling Pathway.

Anti-inflammatory agents are widely used for the treatment of inflammatory diseases. Nevertheless, the associated side effects of the available drugs make it necessary to search for new anti-inflammatory drugs. Here, we investigated the anti-inflammatory activity of solidagenone.

Therapeutic Potential of Bioactive Compounds from Bercht. & J. Presl.

Bercht. & J. Presl has been widely used due to the presence of different bioactive compounds.

Phytochemical analysis of Bercht. & J. Presl and its therapeutic potential for topical use.

Bercht. & J. Presl represents a promising source of new active molecules.

Anti-Inflammatory Activity and Chemical Analysis of Different Fractions from Inflorescence.

Meyen (Compositae) is a species native to South America (Brazil) popularly known as arnica. In Brazilian popular medicine, inflorescences and rhizomes of this plant have been used since the end of the 19th century to replace the exogenous and hepatotoxic L. in the treatment of edema and inflammatory pathologies.

The protective effect of solidagenone from Solidago chilensis Meyen in a mouse model of airway inflammation.

Solidagenone is the main active constituent present in Solidago chilensis Meyen which is used in folk medicine to treat pain and inflammatory diseases. This study aimed to evaluate the anti-inflammatory activity of solidagenone in vitro and in a model of allergic airway inflammation. In vitro studies were performed in activated macrophages and lymphocytes.

Anti-Inflammatory Activity of the Compositae Family and Its Therapeutic Potential.

Compositae is the largest family of flowering plants, with more than 1600 genera and 22 000 species. It has many economic uses in foods, cosmetics, and pharmaceutics. The literature reports its numerous medicinal benefits and recognized anti-inflammatory activity.