Publications by authors named "Simone Montini"

Article Synopsis
  • The lungs are commonly affected by cancer spread, often due to chronic inflammation and injuries that increase cancer risk.
  • Research suggests that lung bacteria play a role in the development of lung cancer, but the relationship between chronic inflammation, bacterial presence, and conditions like bronchiectasis needs further study.
  • The goal of this research is to analyze new data and discuss the current understanding of how these factors influence the lungs, emphasizing the need for early detection and targeted treatments.
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Background: Infection by SARS-CoV2 has become a challenge, especially for immunocompromised patients who show a weaker humoral response to COVID-19 vaccine. Tixagevimab+cilgavimab (Evusheld) is a combination of human monoclonal antibodies that can be used for pre-exposure prophylaxis to prevent infection or disease by SARS-CoV2.

Objectives: Our study aimed to investigate the effectiveness of Evusheld by comparing an Exposed and an Unexposed group.

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A 41-year-old man who currently smokes with previous sporadic use of cocaine and cannabinoids was admitted at the hospital suffering from hemoptysis which had developed 4 days before. The patient was on anticoagulant therapy with rivaroxaban due to paroxysmal atrial fibrillation diagnosed in 2018, for which he had undergone pulmonary vein electrical isolation by radiofrequency and ablation of cavotricuspid isthmus in January 2019. The procedure was completed in July 2019.

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Article Synopsis
  • * Bronchiectasis is associated with various comorbidities and underlying causes, with ongoing research into its inflammatory endotypes and the influence of certain genes on disease progression.
  • * The review aims to compile current knowledge on biomarkers and actionable targets in bronchiectasis, while highlighting gaps in understanding that need to be addressed for improved diagnosis and treatment.
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Pleural mesothelioma is an aggressive disease with diffuse nature, low median survival, and prolonged latency presenting difficulty in prognosis, diagnosis, and treatment. Here, we review all these aspects to underline the progress being made in its investigation and to emphasize how much work remains to be carried out to improve prognosis and treatment.

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