Publications by authors named "Simone K Renner"

Article Synopsis
  • * It highlights a study conducted at Erlangen University Hospital, which included 5,594 patients and over 16,000 examinations in their certified dysplasia unit from July 2014 to December 2019.
  • * Dysplasia units play a crucial role in managing abnormal screening results and serve as the initial contact for patients with genital issues, successfully meeting quality standards for yearly recertification.
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Article Synopsis
  • The study assesses how well clinical findings align with colposcopy-directed punch biopsy results for diagnosing vulvar diseases.
  • Out of 482 biopsies from 420 women, the overall concordance rate between clinical observations and biopsy results was 53.9%, with higher concordance for detecting low and high-grade lesions, as well as vulvar carcinoma.
  • Researchers introduced a new classification system to improve the accuracy and specificity of diagnosing vulvar lesions based on their findings.
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Purpose: Malignancies of the vagina are rare, but colposcopy-directed biopsies play a major role in detecting vaginal intraepithelial lesions. Data of accuracy in detecting neoplasia of the vagina are very rare compared to accuracy in detecting cervical neoplasia. The aim of this study was to evaluate the accuracy of colposcopy-directed biopsy in comparison with clinical findings of the examiner.

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Purpose: Postmenopausal hormone therapy (HT) is known to affect the development of hormone-dependent endometrial carcinoma (type I EC). Several studies on breast and ovarian carcinoma have shown that HT influences the molecular profile and prognostic behavior of these tumors. This study aimed to investigate the influence of prior HT and other risk factors on the prognosis in a cohort of patients with invasive endometrial carcinoma (EC).

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Purpose: The current cervical cancer screening program in Germany recommends that the results showing suspected HPV infection should be further examined in specialized colposcopy units. This study aimed to correlate externally documented Pap smear results with in-house colposcopy-guided Pap cytology results and compare colposcopy-guided biopsy and postoperative histopathology results.

Methods: Clinical data were analyzed from 3627 examinations in 2844 patients who visited a university certified dysplasia unit from 2014 to 2017; 2212 patients underwent complete assessments, including Pap smear, colposcopy, HPV testing, colposcopy-guided biopsy, and/or surgery.

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Purpose: Colposcopy-directed biopsy is a cornerstone method for diagnosing cervical intraepithelial neoplasia. The aim of this study was to evaluate the accuracy of colposcopy-directed biopsy in comparison with definitive surgery.

Methods: The accuracy of colposcopy-directed biopsy was compared with the final histology in relation to different types of transformation zone (TZ), the patient's age, and the examiner's level of training.

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Background: Daysy is a fertility monitor that uses the fertility awareness method by tracking and analyzing the individual menstrual cycle. In addition, Daysy can be connected to the application DaysyView to transfer stored personal data from Daysy to a smartphone or tablet (IOS, Android). This combination is interesting because as it is shown in various studies, the use of apps is increasing patients´ focus on their disease or their health behavior.

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