High-Fluence Epithelium-off Accelerated Pulsed Corneal Cross-linking (15 mW/cm; 7.2 J/cm) for Pediatric Keratoconus: A 3-Year Retrospective Analysis.

Purpose: To assess the safety and efficacy of treatment and secondarily determine the topographic changes, visual outcomes, and demarcation line depth after high-fluence pulsed light accelerated cross-linking (ACXL) in pediatric patients (younger than 18 years) with progressive keratoconus.

Methods: This retrospective analysis included 32 eyes (25 children, aged 11 to 18 years), with progressive keratoconus treated with high-energy epithelium-off pulsed light ACXL (7.2 J/cm, 15 mW/cm, 12 minutes, 2 seconds on/1 second off).