Publications by authors named "Simone Benedetto"

Notification badges are an unexplored category of visual feedback to which we are continuously exposed. This study aims to deepen knowledge on the topic by measuring the behavioral effects of notification badges on a large sample of smartphone users. More precisely, the goal of the study is to observe if the presence of notification badges increases the frequency of clicks on apps.

View Article and Find Full Text PDF

Remote photoplethysmography (rPPG) allows contactless monitoring of human cardiac activity through a video camera. In this study, we assessed the accuracy and precision for heart rate measurements of the only consumer product available on the market, namely the FacereaderTM rPPG by Noldus, with respect to a gold standard electrocardiograph. Twenty-four healthy participants were asked to sit in front of a computer screen and alternate two periods of rest with two stress tests (i.

View Article and Find Full Text PDF

Herpes zoster (HZ) mainly affects older adults and immunocompromised individuals and is usually characterized by a unilateral painful skin rash. Its most common complication, postherpetic neuralgia (PHN), may cause chronic debilitating pain lasting for months or years. This study (ClinicalTrials.

View Article and Find Full Text PDF

Background: We estimated the relative efficacy and safety of vaccines for prevention of herpes zoster (HZ) using network meta-analysis (NMA) based on evidence from randomized controlled trials.

Methods: A systematic literature review evaluated two different HZ vaccines: adjuvanted recombinant zoster vaccine (RZV) and zoster vaccine live (ZVL), with different formulations assessed. Detailed feasibility assessment indicated that a NMA was feasible for efficacy (incidence of HZ and postherpetic neuralgia [PHN]) and safety (serious adverse events [SAE] and reactogenicity [injection-site reactions, systemic reaction]) outcomes.

View Article and Find Full Text PDF

An upsurge in Echovirus 30 (E30) infections, associated with meningitis/meningoencephalitis, has been observed in Denmark, Germany, the Netherlands, Norway and Sweden in the period April to September 2018, compared with 2015-2017. In total, 658 E30 infections among 4,537 enterovirus infections were detected in 15 countries between January and September 2018 and affected mainly newborns and 26-45 year-olds. National public health institutes are reminded to remain vigilant and inform clinicians of the ongoing epidemic.

View Article and Find Full Text PDF

Background: Invasive Group B streptococcus (GBS) is a major cause of serious neonatal infection. Current strategies to reduce early-onset GBS disease have no impact on late-onset disease (LOD). Although GBS LOD is viewed as a sporadic event in the community, LOD arising within the neonatal intensive care unit (ICU) raises questions about mode of acquisition.

View Article and Find Full Text PDF

Fitness trackers are devices or applications for monitoring and tracking fitness-related metrics such as distance walked or run, calorie consumption, quality of sleep and heart rate. Since accurate heart rate monitoring is essential in fitness training, the objective of this study was to assess the accuracy and precision of the Fitbit Charge 2 for measuring heart rate with respect to a gold standard electrocardiograph. Fifteen healthy participants were asked to ride a stationary bike for 10 minutes and their heart rate was simultaneously recorded from each device.

View Article and Find Full Text PDF
Article Synopsis
  • * Testing showed no significant differences in drug concentration or effectiveness between the two formulations, and hypersensitivity reactions (HSRs) were comparable in both groups.
  • * The findings suggest that generic oxaliplatin is a safe and effective alternative to branded formulations, with similar safety profiles in both laboratory and clinical settings.
View Article and Find Full Text PDF

Objectives: The aim of the study was to assess knowledge and attitudes of medical residents working in Università Cattolica del Sacro Cuore, Rome, Italy, on genetic tests for breast and colorectal cancer.

Methods: We distributed self-administered questionnaire to the residents. Logistic regression models were used to evaluate the determinants of knowledge and attitudes towards the tests.

View Article and Find Full Text PDF

In January-March 2013 in England, confirmed measles cases increased in children aged 10-16 years. In April-September 2013, the National Health System and Public Health England launched a national measles-mumps-rubella (MMR) campaign based on data from Child Health Information Systems (CHIS) estimating that approximately 8% in this age group were unvaccinated. We estimated coverage at baseline, and, of those unvaccinated (target), the proportion vaccinated up to 20/08/2013 (mid-point) to inform further public health action.

View Article and Find Full Text PDF

The mass digitization of books is changing the way information is created, disseminated and displayed. Electronic book readers (e-readers) generally refer to two main display technologies: the electronic ink (E-ink) and the liquid crystal display (LCD). Both technologies have advantages and disadvantages, but the question whether one or the other triggers less visual fatigue is still open.

View Article and Find Full Text PDF

Genetic and environmental factors interact in determining the risk of venous thromboembolism (VTE). The risk associated with the polymorphic variants G1691A of factor V (Factor V Leiden, FVL), G20210A of prothrombin (PT20210A) and C677T of methylentetrahydrofolate reductase (C677T MTHFR) genes has been investigated in many studies. We performed a pooled analysis of case-control and cohort studies investigating in adults the association between each variant and VTE, published on Pubmed, Embase or Google through January 2010.

View Article and Find Full Text PDF

Italy has a monitoring system for genetic testing, consisting in a periodic census of clinical and laboratory activities performed in the country. The experience is limited, however, concerning the translation of genomic testing for complex diseases into clinical practice. For the first time the Italian Ministry of Health has introduced a policy strategic plan on genomics and predictive medicine within the 2010-2012 National Prevention Plan.

View Article and Find Full Text PDF
Article Synopsis
  • The study evaluated the quality of guidelines related to genetic susceptibility to breast cancer, analyzing guidelines published until October 2010 using several databases.
  • Four out of thirteen guidelines scored over 50% across all AGREE assessment areas, indicating some, but not universal, strength in quality.
  • The findings suggest that there is significant room for improvement in the guidelines' methodological quality, emphasizing the importance of clear, evidence-based recommendations, particularly given the ethical concerns and costs associated with genetic testing.
View Article and Find Full Text PDF

Background: Apolipoprotein E (ApoE) is a multifunctional protein playing both a key role in the metabolism of cholesterol and triglycerides, and in tissue repair and inflammation. The ApoE gene (19q13.2) has three major isoforms encoded by ε2, ε3 and ε4 alleles with the ε4 allele associated with hypercholesterolemia and the ε2 allele with the opposite effect.

View Article and Find Full Text PDF

Background: We examined the methodological quality of guidelines on colorectal cancer genetic susceptibility syndromes.

Methods: PubMed, EMBASE, and Google were searched up to July 2010. Adjourned guidelines in English were included.

View Article and Find Full Text PDF

The p73 gene (1p36-33) is involved in cancer development through cell growth inhibition by inducing apoptosis in a p53-like manner. The p73 G4C14-to-A4T14 dinucleotide polymorphism, consisting of two single-nucleotide polymorphisms in the non-coding region of exon 2 that are in complete linkage disequilibrium, has been extensively studied in association with cancer risk. We performed a meta-analysis of published studies that examined the association between this p73 G4C14-to-A4T14 polymorphism and cancer by searching for relevant studies on Medline and Embase up to February 28, 2010.

View Article and Find Full Text PDF

In this study we compare the efficacy of three driver's performance indicators based on lateral deviation in detecting significant on-road performance degradations while interacting with a secondary task: the High Frequency Component of steering wheel (HFC), and two indicators described in ISO/DIS 26022 (2007): the Normative and the Adapted Lane Change Test (LCT). Sixteen participants were asked to perform a simulated lane-change task while interacting, when required, with a visual search task with two levels of difficulty. According to predictions, results showed that the Adapted LCT indicator, taking into consideration individual practices in performing the LCT, succeeded in discriminating between single and dual task conditions.

View Article and Find Full Text PDF

Objective: To determine the prognostic influence of race/ethnicity on survival among patients infected with HIV infection.

Background: In the U.S.

View Article and Find Full Text PDF

A PHP Error was encountered

Severity: Warning

Message: fopen(/var/lib/php/sessions/ci_sessionnqbs85f1o9dgb3vs5c495de995bitcod): Failed to open stream: No space left on device

Filename: drivers/Session_files_driver.php

Line Number: 177

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Failed to read session data: user (path: /var/lib/php/sessions)

Filename: Session/Session.php

Line Number: 137

Backtrace:

File: /var/www/html/index.php
Line: 316
Function: require_once