Publications by authors named "Simona Steinmann"
Article Synopsis
- * Results showed a significant reduction in the Psoriasis Area and Severity Index (PASI) after 3 and 18 months, with many patients achieving low PASI scores, indicating effective treatment.
- * Improvements in quality of life were noted, and no patients discontinued treatment due to adverse events, suggesting that tildrakizumab has a strong safety profile in a real-world setting.
Background: Psoriasis is a disease that often requires prolonged systemic treatment. It is important to determine the safety of available therapies. There is currently little insight into sex-specific differences in the safety of systemic psoriasis therapies.
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- Primary localized cutaneous amyloidosis (PLCA) is a skin condition characterized by amyloid protein deposits without affecting other body systems, with four notable subtypes: lichen, macular, biphasic, and nodular amyloidosis, primarily impacting Latin American and Asian populations.
- A study reviewed 37 confirmed PLCA cases, finding lichen amyloidosis was the most common subtype, and highlighted demographic info and treatment responses, noting that 59.4% of patients had higher skin phototypes.
- The most effective treatment combination was UVA1 phototherapy with high-potency corticosteroids, leading to complete symptom clearance in a small subset of patients, while lower-potency treatments showed less effectiveness.