Publications by authors named "Simona Migliazza"
Article Synopsis
- The study looks at how different types of medications, called biological drugs and biosimilars, affect health care costs for patients with certain diseases, especially in rheumatology.
- Researchers examined 145 patients and found that most were using the original biological drugs instead of the biosimilars, even though patients using biosimilars showed better adherence to treatment.
- The total health costs for these patients over one year was quite high, with a large portion going toward medications, and the study suggests that better communication among health professionals could help more people use biosimilars.
Background And Aim: Asthma and chronic obstructive pulmonary disease (COPD) are leading causes of morbidity and mortality worldwide. Globally, 545 million people suffer from chronic respiratory diseases with a wide geographical variability. Risk factors for asthma are both genetic and related to several environmental factors (internal and external pollutants); these also have an important role in the occurrence of COPD.
View Article and Find Full Text PDFInfluence of initial glucocorticoid co-medication on mortality and hospitalization in early inflammatory arthritis: an investigation by record linkage of clinical and administrative databases.
Arthritis Res Ther
June 2022
Article Synopsis
- This study explored the relationship between low-dose glucocorticoids (GCs) and mortality in patients with early arthritis, specifically rheumatoid arthritis (RA) or undifferentiated arthritis, using linked clinical and administrative data.
- A total of 449 patients were enrolled, with a follow-up period averaging about 104 months; 11.36% of participants died during the study.
- The analysis indicated that low-dose GCs did not significantly predict mortality, regardless of dosage (≤7.5 mg/day or >7.5 mg/day), suggesting no clear impact on overall survival in these patients.
The COVID-19 pandemic had an unfavorable impact on overall mortality in Italy, with the strongest consequences in northern Italy. Scant data are available on cause-specific mortality. This study aims at investigating the impact of the pandemic on the overall and cause-specific mortality in one province in northern Italy, Pavia.
View Article and Find Full Text PDFObjectives: to evaluate time and spatial distribution of hospitalization due to neurological diseases in the province of Pavia (Lombardy Region, Northern Italy).
Design: ecological study.
Setting And Participants: the study was performed on aggregate data of people residing in the province of Pavia in the period 2005-2014.
Background: Acute kidney injury (AKI) is emerging as a predictor of poor stroke outcome, however, it is often not recognized. The aim of our study was to evaluate post-stroke AKI burden, AKI risk factors and their influence in post-stroke outcome.
Methods: From 2013 to 2016, 440 individuals with stroke diagnosis admitted in Stroke Unit, Foundation IRCCS Policlinico San Matteo (Pavia, Italy), were retrospectively enrolled.
Objectives: To develop and validate a new algorithm to identify patients with rheumatoid arthritis (RA) and estimate disease prevalence using administrative health databases (AHDs) of the Italian Lombardy region.
Design: Case-control and cohort diagnostic accuracy study.
Methods: In a randomly selected sample of 827 patients drawn from a tertiary rheumatology centre (training set), clinically validated diagnoses were linked to administrative data including diagnostic codes and drug prescriptions.