Inadvertent Intoxication with Salbutamol, Treated with Hemodialysis: A Case Report and Brief Review of the Literature.

Introduction: Salbutamol is a moderately selective beta-2-adrenergic agonist. Various side effects can occur because of beta-1 and beta-2 receptor activation. Due to the large volume of distribution, it is not considered dialyzable.

CTSS activation coexists with CD40 activation in human atheroma: evidence from plasma mRNA analysis.

Objectives: By the analysis of plasma mRNA levels, we tested the hypothesis that, in human atheroma, CTSS activation coexists with activation of CD40.

Design And Methods: mRNAs were isolated from plasma of patients with coronary atherosclerosis and quantified by real-time RT-PCR.

Results: CTSS mRNA levels correlated with CD40 mRNA levels, independently of observed traditional risk factors for atherosclerosis and pharmacological treatment.

Increased DAPK1 but decreased CCL2 plasma levels of nucleic acids in patients with stable angina.

Introduction: We hypothesized that patients with stable angina have increased plasma levels of mRNA from genes responsible for atherosclerotic plaque development and destabilisation, i.e. from death-associated protein kinase (DAPK1) and monocyte chemotactic protein-1 (CCL2).

Plasminogen activator inhibitor-1, which is released from blood product transfusions, might be associated with (sub)acute thrombosis after coronary dilatation and stenting: a case report.

We present the case of a 71-year-old man who suffered bleeding complications after coronary dilatation and stenting, necessitating a substantial number of platelet and whole blood transfusions in the following days. Postmortem analysis of plasma samples obtained after the transfusions revealed unexpectedly elevated levels of plasminogen activator inhibitor-1 (PAI-1) antigen and activity associated with a nonmeasurable euglobulin clot lysis time, disclosing extreme hypofibrinolysis, which might facilitate coronary thrombosis. The patient died suddenly on day 6, very likely due to coronary thrombosis.