Nationwide randomised trial evaluating elective neck dissection for early stage oral cancer (SEND study) with meta-analysis and concurrent real-world cohort.

Background: Guidelines remain unclear over whether patients with early stage oral cancer without overt neck disease benefit from upfront elective neck dissection (END), particularly those with the smallest tumours.

Methods: We conducted a randomised trial of patients with stage T1/T2 N0 disease, who had their mouth tumour resected either with or without END. Data were also collected from a concurrent cohort of patients who had their preferred surgery.

Hyperparathyroidism jaw tumour syndrome: a pictoral review.

Unlabelled: Hyperparathyroidism jaw tumour syndrome is a rare autosomal dominant inherited endocrine neoplasia syndrome, which predisposes carriers to develop a triad of multiple ossifying fibromas of the maxilla and mandible, parathyroid adenomas and carcinomas (with consequent hyperparathyroidism) as well as renal and uterine tumours. The prevalence of this condition is unknown. Patients typically present initially with symptoms and signs of a jaw tumour.

Smoking habits in patient's who have been treated for an oral cancer: validation of self-report using saliva cotinine.

There is a perception amongst health care professional that patients under-report their smoking habits. The aim of this study was to validate self-reported smoking habits in patients who have been treated for an oral cancer using saliva cotinine. In a cross-sectional study100 consecutive patients attending a maxillofacial oncology clinic completed a smoking related questionnaire following which a saliva sample was obtained.