Publications by authors named "Simon Viville"
Article Synopsis
- A study conducted in France updated the epidemiology of perioperative anaphylaxis, a rare but serious allergic reaction occurring during surgeries, highlighting its changing nature influenced by clinical practices and environment.*
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- Out of 765 cases analyzed, a significant portion (56%) were severe reactions, mainly caused by neuromuscular blocking agents (60%), with antibiotics like cefazolin also being a notable trigger.*
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- The study emphasizes the need for ongoing surveillance of perioperative anaphylaxis, particularly due to the increasing frequency of reactions to antibiotics and the unknown reasons behind cefazolin sensitization.*
Clin Exp Allergy
February 2022
Article Synopsis
- * Researchers analyzed data from 162 patients, noting that 80.8% experienced severe reactions and identified an optimal tryptase cut-off of 9.8 μg/L to differentiate positive allergy tests from negative ones.
- * A higher tryptase level of 33 μg/L provided a strong positive predictive value (PPV) of 93%, while utilizing specific formulas to assess serial tryptase levels improved diagnostic accuracy.
