Publications by authors named "Simon T Kueppers"
Among heart transplant (HT) recipients, a reduced immunological response to SARS-CoV-2 vaccination has been reported. We aimed to assess the humoral and T-cell response to SARS-CoV-2 vaccination in HT recipients to understand determinants of immunogenicity. HT recipients were prospectively enrolled from January 2021 until March 2022.
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- * Strategies include gene editing to reduce cell antigenicity, immunosuppression of the recipient, and using histocompatibility-matched cells from banks.
- * Research focused on H-Y antigens, which come from the Y chromosome and may be influenced by the donor's gender, found that these antigens elicit immune responses in female mice receiving embryonic or endothelial stem cells.