Publications by authors named "Simon Schnabl"
Article Synopsis
- - Small nucleolar RNAs (snoRNAs) are non-coding RNAs crucial for the creation of ribosomes and spliceosomes by targeting specific sites on ribosomal and spliceosomal RNAs for modifications, though many snoRNAs still lack comprehensively identified functions.
- - An enhanced method called chimeric eCLIP was developed to investigate snoRNA-target RNA interactions, confirming known interactions in cell lines and discovering new ones, particularly for orphan snoRNAs.
- - The study found that snoRNA complexes with certain accessory proteins, such as WDR43 and NOLC1, have unique interactions that influence ribosome and spliceosome biogenesis, highlighting the dual role of snoRNAs in modifying RNA and regulating splicing processes.
