Publications by authors named "Simon Schick"

Article Synopsis
  • Biobased polymers like PLA and PBS can naturally degrade in specific environments, and their degradation efficiency is influenced by fiber surface properties affecting polymer accessibility.
  • The study compared the degradation of PLA and PBS fibers with different cross-sections by subjecting them to hydrolysis and UV exposure, followed by laboratory tests to assess their degradation.
  • Results showed PLA fibers degraded completely, while PBS fibers remained intact despite larger surface areas; this highlights that analyzing single degradation mechanisms does not accurately predict real-world material behavior.
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Article Synopsis
  • * Two bacterial strains are designed to complement each other: one produces anthranilate (ANT), which the other converts to tryptophan (TRP) and then to VIO, showcasing a division of labor.
  • * The research highlights the influence of different carbon sources on co-culture stability and VIO production, with D-xylose resulting in the best outcomes, paving the way for scaling up production in bioreactors.
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Biodegradable biopolymers such as polylactic acid and polybutylene succinate are sustainable alternatives to traditional petroleum-based plastics. However, the factors affecting their degradation must be characterized in detail to enable successful utilization. Here we compared the extruder dwell time at three different melt-spinning scales and its influence on the degradation of both polymers.

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The concept of modular synthetic co-cultures holds considerable potential for biomanufacturing, primarily to reduce the metabolic burden of individual strains by sharing tasks among consortium members. However, current consortia often show unilateral relationships solely, without stabilizing feedback control mechanisms, and are grown in a shared cultivation setting. Such 'one pot' approaches hardly install optimum growth and production conditions for the individual partners.

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Manufacturers of technical polymers must increasingly consider the degradability of their products due to the growing public interest in topics such as greenhouse gas emissions and microplastic pollution. Biobased polymers are part of the solution, but they are still more expensive and less well characterized than conventional petrochemical polymers. Therefore, few biobased polymers with technical applications have reached the market.

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In nature, microorganisms often reside in symbiotic co-existence providing nutrition, stability, and protection for each partner by applying "division of labor." This principle may also be used for the overproduction of targeted compounds in bioprocesses. It requires the engineering of a synthetic co-culture with distributed tasks for each partner.

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