Publications by authors named "Simon Parke"

Article Synopsis
  • The initiative aimed to engage children affected by cancer, survivors, families, and healthcare professionals to identify and prioritize research questions that could shape future studies on childhood cancer.
  • An online survey gathered over 1,200 potential questions, which were then refined and shortlisted through surveys and workshops with participants, resulting in a final consensus on the Top 10 priorities.
  • The most significant concern identified was the need for more effective and less burdensome treatments for children with cancer, emphasizing a focus on improving patient care and outcomes.
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Kawasaki disease (KD) is an acute inflammatory vasculitis that occurs worldwide and disproportionately affects male children, most commonly between the ages of 6 months and 5 years. KD can present with only a few features and thus be difficult to diagnose, particularly in the youngest and oldest patients. We describe a 12-week-old Caucasian female infant who presented with rash and fever but no other features of KD, who developed giant coronary artery aneurysms.

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Pigmented villonodular synovitis (PVNS), a condition of synovial hyperproliferation that mostly affects large joints, is rare in children and conventionally lacks systemic symptoms. This report describes a complex paediatric patient who underwent bone marrow transplantation to control the accelerated phase of the Chediak-Higashi syndrome. Diffuse PVNS developed in one knee 2.

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