Publications by authors named "Simon M Freeman"
Article Synopsis
- The study examines the safety of radiation treatment for benign tumors in patients with NF2-related schwannomatosis, finding an increased risk of subsequent malignancies or malignant progression in those who received radiation compared to untreated patients.
- Out of 1345 NF2 patients studied, 266 received radiation, leading to a malignancy rate of approximately 6%, as opposed to less than 1% in those not treated with radiation.
- The findings suggest that NF2 patients should not receive radiation as the first treatment option for benign tumors due to the associated risks and should be informed about the significant risk of developing new malignancies.
Background: The Manchester criteria for neurofibromatosis type 2 (NF2) include a range of tumors, and gliomas were incorporated in the original description. The gliomas are now widely accepted to be predominantly spinal cord ependymomas.
Objective: To determine whether these gliomas include any cases of malignant glioma (WHO grade III and IV) through a database review.
Objectives: The aim of this study was to quantify the benefit gained from cochlear implantation in pre- or peri-lingually deafened patients who were implanted as adults Methods: This was a retrospective case-control study. Auditory (BKB/CUNY/3AFC/Environmental sounds), quality of life (GBI/HUI3) and cognitive (customized questionnaire) outcomes in 26 late implanted pre- or peri-lingually deafened adults were compared to those of 30 matched post-lingually deafened, traditional cochlear implant users.
Results: There was a statistically significant improvement in all scores in the study group following cochlear implantation.