Effect of Health Literacy on Antiviral Treatment of Hepatitis B: Instrumental Variable Analysis.

Background: China is a country with a high burden of hepatitis B (Hep B) but a low treatment rate. One of the key reasons for the low treatment rate is the inadequate health literacy (HL) of the people, which may affect the awareness and knowledge of Hep B and its treatment, as well as the ability to actively and correctly seek medical resources.

Objective: This study analyzed how HL contributed to the scale-up of antiviral treatment of Hep B in China.

Uptake of hepatitis C direct-acting antiviral treatment in China: a retrospective study from 2017 to 2021.

Background: Direct-acting antivirals (DAAs) for hepatitis C treatment in China became available since 2017. This study expects to generate evidence to inform decision-making in a nationwide scale-up of DAA treatment in China.

Methods: We described the number of standard DAA treatment at both national and provincial levels in China from 2017 to 2021 based on the China Hospital Pharmacy Audit (CHPA) data.

Uptake of hepatitis B antiviral treatment: A panel data analysis of 31 provinces in China (2013-2020).

Background: China has made substantial efforts aimed to promote the uptake of antiviral treatment of hepatitis B (HB). It is unclear whether these policies achieved the desired impact. This study adopted medicines procurement data from 31 provinces to generate the first evidence about the number of standard antiviral treatment of HB overtime at both national and provincial levels in China.

Hydrogen Shifts in Aryl Radicals and Diradicals: The Role of m-Benzynes.

Density functional and coupled cluster results are presented for hydrogen shifts in radicals derived from polycyclic aromatic hydrocarbons (PAHs) and for rearrangement mechanisms for several phenylenes. RCCSD(T)/cc-pVDZ//UBLYP/cc-pVDZ free energy barriers for 1,4-H shifts at 298 K are consistently predicted to be ca. 25 kcal/mol, whereas barriers for 1,5- and 1,6-shifts range from 6 to 28 kcal/mol.