Publications by authors named "Simon Lee Hetherington"
Article Synopsis
- The study aimed to assess if a very early invasive strategy (IS) with possible revascularisation improves outcomes compared to standard care for high-risk patients with non-ST-elevation acute coronary syndrome (NSTE-ACS).
- 425 patients were randomly assigned to either very early IS (within 90 minutes) or standard IS (within 72 hours), but the trial was halted early due to slow recruitment amid the COVID-19 pandemic.
- At 12 months, there were no significant differences in clinical outcomes between the two groups, although the very early IS group had a shorter hospital stay.
Introduction: Bicuspid aortic valve (BAV) affects 1% of the general population. was the first gene associated with BAV. The proportion of familial and sporadic BAV disease attributed to mutations has not been estimated.
View Article and Find Full Text PDFBackground: Remote ischaemic conditioning (rIC) is a cardioprotective tool which has shown promise in preclinical and clinical trials in the context of acute ischaemia. Repeated rIC post myocardial infarction may provide additional benefits which have not previously been tested clinically.
Methods: The trial assessed the role of daily rIC in enhancing left ventricular ejection fraction (LVEF) recovery in patients with impaired LVEF (<45%) after ST segment elevation myocardial infarction (STEMI) treated with primary percutaneous coronary intervention (P-PCI).