Language structure reflects biases in pattern learning across domains and modalities.

A central goal for psychological science is the explanation of variation in human behaviour. In the domain of language, patterns of cross-linguistic variation have been extensively documented, but there has been vigorous debate over how to explain them. A particularly contentious question is whether constraints on linguistic variation are driven by properties of the human mind that are specific to language or domain-general.

Increased water temperature contributes to a chondrogenesis response in the eyes of spotted wolffish.

Adult vertebrate cartilage is usually quiescent. Some vertebrates possess ocular scleral skeletons composed of cartilage or bone. The morphological characteristics of the spotted wolffish (Anarhichas minor) scleral skeleton have not been described.

Predictability and Variation in Language Are Differentially Affected by Learning and Production.

General principles of human cognition can help to explain why languages are more likely to have certain characteristics than others: structures that are difficult to process or produce will tend to be lost over time. One aspect of cognition that is implicated in language use is working memory-the component of short-term memory used for temporary storage and manipulation of information. In this study, we consider the relationship between working memory and regularization of linguistic variation.

Evaluating the Relative Importance of Wordhood Cues Using Statistical Learning.

Identifying wordlike units in language is typically done by applying a battery of criteria, though how to weight these criteria with respect to one another is currently unknown. We address this question by investigating whether certain criteria are also used as cues for learning an artificial language-if they are, then perhaps they can be relied on more as trustworthy top-down diagnostics. The two criteria for grammatical wordhood that we consider are a unit's free mobility and its internal immutability.

Cultural evolution creates the statistical structure of language.

Human language is unique in its structure: language is made up of parts that can be recombined in a productive way. The parts are not given but have to be discovered by learners exposed to unsegmented wholes. Across languages, the frequency distribution of those parts follows a power law.

Kruppel-family zinc finger proteins as emerging epigenetic biomarkers in head and neck squamous cell carcinoma.

Background: Krüppel-type zinc finger protein genes located on chromosome 19q13 are aberrantly hypermethylated with high frequency in all anatomic sub-sites of head and neck cancers as well as other epithelial tumours resulting in decreased expression.

Methods: We examined prognostic significance of ZNF154 and ZNF132 expression and DNA methylation in independent patient cohort of about 500 head and neck cancer patients in the Cancer Genome Atlas (TCGA). We also overexpressed these genes in HEK-293 cells, as well as the oral cancer cell line UM-SCC-1.

Documenting a Reduction in Signing Space in Nicaraguan Sign Language Using Depth and Motion Capture.

In this paper, we use motion tracking technology to document the birth of a brand new language: Nicaraguan Sign Language. Languages are dynamic entities that undergo change and growth through use, transmission, and learning, but the earliest stages of this process are generally difficult to observe as most languages have been used and passed down for many generations. Here, we observe a rare case of language emergence: the earliest stages of the new sign language in Nicaragua.

The role of artificial intelligence in the treatment of obstructive sleep apnea.

Background: The first-line and most common treatment for obstructive sleep apnea is nasal continuous positive airway pressure, which serves as a pneumatic splint to stabilize the upper airway and is effective when used with appropriate adherence. Continuous positive airway pressure compliance rates remain significantly low despite machine improvements and compliance intervention. Other treatment options include oral appliances, myofunctional therapy, and surgery.

Intraoperative video recording in otolaryngology for surgical education: evolution and considerations.

Background: Otolaryngology is a surgical speciality well suited for the application of intraoperative video recording as an educational tool considering the number procedures within the speciality that utilize digital technology. Intraoperative recording has been utilized in endoscopic surgeries and in evaluating technique in mastoidectomy, myringotomy and grommet insertion. The impact of intra-operative video recording in otolaryngology education is vast in creating access to surgical videos for preparation outside the operating room to individualized coaching and assessment.

The Effects of Iconicity and Conventionalization on Word Order Preferences.

Of the six possible orderings of the three main constituents of language (subject, verb, and object), two-SOV and SVO-are predominant cross-linguistically. Previous research using the silent gesture paradigm in which hearing participants produce or respond to gestures without speech has shown that different factors such as reversibility, salience, and animacy can affect the preferences for different orders. Here, we test whether participants' preferences for orders that are conditioned on the semantics of the event change depending on (i) the iconicity of individual gestural elements and (ii) the prior knowledge of a conventional lexicon.

Adjective position and referential efficiency in American Sign Language: Effects of adjective semantics, sign type and age of sign exposure.

Previous research has pointed at communicative efficiency as a possible constraint on language structure. Here we investigated adjective position in American Sign Language (ASL), a language with relatively flexible word order, to test the incremental efficiency hypothesis, according to which both speakers and signers try to produce efficient referential expressions that are sensitive to the word order of their languages. The results of three experiments using a standard referential communication task confirmed that deaf ASL signers tend to produce absolute adjectives, such as color or material, in prenominal position, while scalar adjectives tend to be produced in prenominal position when expressed as lexical signs, but in postnominal position when expressed as classifiers.

Engaging communities in addressing air quality: a scoping review.

Background: Exposure to air pollution has a detrimental effect on health and disproportionately affects people living in socio-economically disadvantaged areas. Engaging with communities to identify concerns and solutions could support organisations responsible for air quality control, improve environmental decision-making, and widen understanding of air quality issues associated with health. This scoping review aimed to provide an overview of approaches used to engage communities in addressing air quality and identify the outcomes that have been achieved.

The Acute Stroke Therapy by Inhibition of Neutrophils study - Key features and impact.

The Acute Stroke Therapy by Inhibition of Neutrophils (ASTIN) study, initiated in November of the year 2000, is now widely recognized as having been a landmark study in the history of clinical trials. We look at why this is the case by considering its key features and impact. These key features are: the use of Bayesian design and analysis; the use of the normal dynamic linear model; the response adaptive nature of the study; the use of real-time dosing decisions; and the use of an integrated model to predict 90-day response on the Scandinavian Stroke Scale.

From improvisation to learning: How naturalness and systematicity shape language evolution.

Silent gesture studies, in which hearing participants from different linguistic backgrounds produce gestures to communicate events, have been used to test hypotheses about the cognitive biases that govern cross-linguistic word order preferences. In particular, the differential use of SOV and SVO order to communicate, respectively, extensional events (where the direct object exists independently of the event; e.g.

Investigating Word Order Emergence: Constraints From Cognition and Communication.

How do cognitive biases and mechanisms from learning and use interact when a system of language conventions emerges? We investigate this question by focusing on how transitive events are conveyed in silent gesture production and interaction. Silent gesture experiments (in which participants improvise to use gesture but no speech) have been used to investigate cognitive biases that shape utterances produced in the absence of a conventional language system. In this mode of communication, participants do not follow the dominant order of their native language (e.

Barriers of artificial intelligence implementation in the diagnosis of obstructive sleep apnea.

Background: Obstructive sleep apnea is a common clinical condition and has a significant impact on the health of patients if untreated. The current diagnostic gold standard for obstructive sleep apnea is polysomnography, which is labor intensive, requires specialists to utilize, expensive, and has accessibility challenges. There are also challenges with awareness and identification of obstructive sleep apnea in the primary care setting.

Cumulative cultural evolution, population structure and the origin of combinatoriality in human language.

Language is the primary repository and mediator of human collective knowledge. A central question for evolutionary linguistics is the origin of the combinatorial structure of language (sometimes referred to as duality of patterning), one of language's basic design features. Emerging sign languages provide a promising arena to study the emergence of language properties.

Conceptual Similarity and Communicative Need Shape Colexification: An Experimental Study.

Colexification refers to the phenomenon of multiple meanings sharing one word in a language. Cross-linguistic lexification patterns have been shown to be largely predictable, as similar concepts are often colexified. We test a recent claim that, beyond this general tendency, communicative needs play an important role in shaping colexification patterns.

Chondroma of the Nasal Septum.

Chondromas are benign cartilaginous tumours that rarely occur in the head and neck region. Only a limited number of cases have been reported involving the nasal septum. Here we report a case of a 55-year-old male that presented with a suspicious lesion involving his nasal septum and columella.

Simplicity and informativeness in semantic category systems.

Recent research has shown that semantic category systems, such as color and kinship terms, find an optimal balance between simplicity and informativeness. We argue that this situation arises through pressure for simplicity from learning and pressure for informativeness from communicative interaction, two distinct pressures that often (but not always) pull in opposite directions. Another account argues that learning might also act as a pressure for informativeness, that learners might be biased toward inferring informative systems.

Benign Palatine Tonsil Volume Variation Following Bilateral Tonsillectomy in Adults.

Background There is a lack of data on normal size discrepancy in benign tonsils. The current school of thought for otolaryngologists is to remove tonsils that look clinically asymmetric on the basis of occult malignancy. However, many of these tonsils turn out to be benign after microscopic evaluation.

Evolving artificial sign languages in the lab: From improvised gesture to systematic sign.

Recent work on emerging sign languages provides evidence for how key properties of linguistic systems are created. Here we use laboratory experiments to investigate the contribution of two specific mechanisms-interaction and transmission-to the emergence of a manual communication system in silent gesturers. We show that the combined effects of these mechanisms, rather than either alone, maintain communicative efficiency, and lead to a gradual increase of regularity and systematic structure.