Publications by authors named "Simon J Ledingham"
Article Synopsis
- Neutrophil activation post-cardiopulmonary bypass (CPB) can lead to lung complications, and this study investigates whether the healthy lung can modify pro-inflammatory neutrophils.
- Using a unique model involving bilateral pulmonary vein sampling during surgery, 17 patients undergoing coronary artery bypass grafting were analyzed to compare neutrophil function between ventilated and deflated lungs.
- Results showed no significant difference in neutrophil activity between samples from ventilated vs. deflated lungs, although plasma cytokines increased notably due to CPB.
