Incorporating information in deep learning models for quantitative susceptibility mapping via adaptive convolution.

Quantitative susceptibility mapping (QSM) has attracted considerable interest for tissue characterization (e.g., iron and calcium accumulation, myelination, venous vasculature) in the human brain and relies on extensive data processing of gradient-echo MRI phase images.

ABC-HuMi: the Atlas of Biosynthetic Gene Clusters in the Human Microbiome.

The human microbiome has emerged as a rich source of diverse and bioactive natural products, harboring immense potential for therapeutic applications. To facilitate systematic exploration and analysis of its biosynthetic landscape, we present ABC-HuMi: the Atlas of Biosynthetic Gene Clusters (BGCs) in the Human Microbiome. ABC-HuMi integrates data from major human microbiome sequence databases and provides an expansive repository of BGCs compared to the limited coverage offered by existing resources.

Advantages and disadvantages of the three-dimensional metal printed orthodontic appliances.

Orthodontic digitalization has progressed steadily. Recently, three-dimensional metal printing has revolutionized the way appliances are designed and manufactured. The process offers several advantages over the conventional analog process for both the orthodontic team and the patients.

Direct printed removable appliances: A new approach for the Twin-block appliance.

Removable appliances are an important part of orthodontic treatment. The Twin-block is widely used for Class II correction. Traditionally, an impression, bite registration, and mounted plaster casts are required to fabricate the acrylic appliance, which usually requires a specialized laboratory.

CAD-CAM design and 3-dimensional printing of mini-implant retained orthodontic appliances.

The objective of this article was to illustrate the digital process in the custom fabrication of metallic mini-implant supported appliances. An implant-supported appliance was produced for a patient using a CAD-CAM procedure without a physical impression or a printed model. The work flow consisted of mini-implant insertion into the palate, recording an intraoral digital scan, digital design with incorporation of a scanned expansion mechanism, direct 3-dimensional metal printing via laser melting, laser welding of the hyrax mechanism, insertion, and activation of the appliance.

Computer-aided design and manufacture of hyrax devices: Can we really go digital?

The aim of this pilot study was to illustrate the feasibility of a new digital procedure to fabricate metallic orthodontic appliances. Hyrax appliances for rapid palatal expansion were produced for 3 patients using a CAD/CAM procedure without physical impressions or printed models. The work flow consisted of intraoral scanning, digital design with incorporation of a scanned prefabricated expansion screw, direct 3-dimensional metal printing via laser melting, welding of an expansion screw, insertion, and finally activation in the patients' mouths.