Publications by authors named "Simon Gloger"
Article Synopsis
- Conversions from robot-assisted partial nephrectomy to more invasive surgeries happen in about 1-5% of cases, and this study looks at what could predict these conversions.
- The research analyzed 2,549 patients operated on by 25 surgeons, finding a 3.5% conversion rate linked to factors like older age, higher BMI, tumor size, and the surgeon’s experience.
- The study concludes that both patient characteristics and surgical expertise significantly impact the likelihood of conversion, suggesting that better training could enhance outcomes and allow for more kidney-sparing procedures.
Article Synopsis
- - The study aimed to analyze factors affecting postoperative renal function (PRF) following robot-assisted partial nephrectomy for patients with multiple kidney tumors, using data from 132 surgeries and assessing both patient and surgical influences on outcomes.
- - Key findings included that most patients had two tumors, the average surgery lasted 175 minutes, and that the majority of surgeries met trifecta criteria, indicating successful outcomes in terms of cancer control, renal preservation, and complications.
- - Factors such as warm ischemia time, body mass index (BMI), and preoperative kidney function were found to impact kidney function loss post-surgery, with BMI and comorbidities being significant predictors of acute kidney injury during hospitalization.
Introduction: Aquablation and holmium laser enucleation of the prostate (HoLEP) have evolved as established therapeutic options for men with benign prostatic obstruction (BPO). We sought to compare the rates of incidental prostate cancer (iPCa) after aquablation and HoLEP.
Methods: At our center, between January 2020 and November 2022, 317 men underwent aquablation, and 979 men underwent HoLEP for BPO.
Context: Symptomatic lymphocele (sLC) occurs at a frequency of 2-10% after robot-assisted radical prostatectomy (RARP) with pelvic lymph node dissection (PLND). Construction of bilateral peritoneal interposition flaps (PIFs) subsequent to completion of RARP + PLND has been introduced to reduce the risk of lymphocele, and was initially evaluated on the basis of retrospective studies.
Objective: To conduct a systematic review and meta-analysis of only randomized controlled trials (RCTs) evaluating the impact of PIF on the rate of sLC (primary endpoint) and of overall lymphocele (oLC) and Clavien-Dindo grade ≥3 complications (secondary endpoints) to provide the best available evidence.
Lymphoceles (LC) occur in up to 60% after robot-assisted radical prostatectomy (RARP) and pelvic lymphadenectomy (PLND). In 2-10%, they are symptomatic and may cause complications and require treatment. Data on risk factors for the formation of lymphoceles after RARP and PNLD remain sparse in the urologic literature and are inconclusive to date.
View Article and Find Full Text PDFBackground: Robot-assisted partial nephrectomy (RAPN) is a challenging procedure that is influenced by a multitude of factors.
Objective: To assess the impact of prior surgical experience on perioperative outcomes in RAPN.
Design Setting And Participants: In this retrospective multicenter study, results for 2548 RAPNs performed by 25 surgeons at eight robotic referral centers were analyzed.
Purpose: The purpose of this study was to investigate the effect of a surgically constructed bilateral peritoneal flap (PIF) as an adjunct to robot-assisted radical prostatectomy (RARP) and pelvic lymph node dissection (PLND) on the incidence of lymphoceles.
Materials And Methods: A total of 530 men with localized prostate cancer underwent a RARP with bilateral extended standardized PLND in a prospective randomized controlled trial. In group A, a PIF was created by suturing the margins of the bladder peritoneum to the ipsilateral endopelvic fascia at 2 points on each side.
Introduction: To compare the surgical methods of Aquablation followed by selective hemostasis by bipolar cauterization with holmium laser enucleation of the prostate (HoLEP) with regard to the risk of perioperative bleeding complications.
Materials And Methods: A retrospective comparison was carried out on a total of 382 patients who had undergone either Aquablation (n = 167) or HoLEP (n = 215) at our hospital between April 2018 and July 2020. The following were studied: Hb loss, the need for packed red blood cell transfusions and surgical revisions due to bleeding from the prostatic fossa.
Article Synopsis
- Aromatase inhibitors like letrozole, which lower estradiol levels, may cause memory issues in women by inducing changes in the brain.
- Letrozole treatment in female mice led to a rapid decline in long-term potentiation (LTP) and cofilin phosphorylation, both important for memory formation and maintenance.
- The study found that the negative effects on brain structure and function were similar in both female and male mice, but the response intensity varied between genders, suggesting significant implications for memory impairments in women using letrozole.