The Role of Parental Reflective Functioning in Associations between Daily Autonomy-Relevant Parenting, Parenting Stress, and Early and Middle Adolescents' Day-to-Day Difficulties.

Autonomy-supportive parenting benefits adolescents' psychosocial adjustment, but daily fluctuations in adolescent difficulties and parenting stress can reduce autonomy support and lead to more controlling practices. However, currently it is not yet well understood why some parents seem better able to deal with the daily upheavals characteristic of adolescence, while other parents may resort to controlling practices. To address this gap, the present studies examined the moderating role of parental reflective functioning (i.

Understanding Parenting Stress in Adoptive Parents: A Longitudinal Multilevel Study of Parents' Self-Criticism, Child Negative Emotionality, and Child Age at Placement.

Introduction: Research on parenting stress in adoptive parents during the early years post-placement reveals significant variability, yet few studies examine both parent- and child-related factors. This study investigates the role of the personality dimension of self-criticism and perceived negative child emotionality in relation to parenting stress during the first four years after transnational adoption. Additionally, it explores the moderating effect of child age at placement, a key factor associated with early adversity.

Randomized Controlled Immunotherapy Clinical Trials for GBM Challenged.

Immunotherapies represent a promising strategy for glioblastoma multiforme (GBM) treatment. Different immunotherapies include the use of checkpoint inhibitors, adoptive cell therapies such as chimeric antigen receptor (CAR) T cells, and vaccines such as dendritic cell vaccines. Antibodies have also been used as toxin or radioactive particle delivery vehicles to eliminate target cells in the treatment of GBM.