The effect of fatigability on Expanded Disability Status Scale components in multiple sclerosis.

Introduction: The Expanded Disability Status Scale (EDSS) is the most widely used disability measure in multiple sclerosis (MS). The effect of fatigability on EDSS components has been underreported to date.

Objective: We investigated daytime variability in EDSS score and EDSS components – functional scores (FS) and walking distance (WD) up to 500 m, in MS patients who underwent a standardized fatiguing exercise.