Publications by authors named "Simon D Chen"

Purpose: To investigate the molecular mechanism by which triamcinolone acetonide (TA) may reduce edema in a porcine model of branch retinal vein occlusion (BRVO).

Design: Animal study.

Method: After baseline ophthalmoscopic examination and fundus photography, a BRVO was created photothrombotically in each eye of 6 pigs, using argon green photocoagulation and intravenous Rose Bengal.

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Scedosporium apiospermum is an increasingly recognized cause of endogenous fungal endophthalmitis in immunocompromised patients. The authors describe two patients with endogenous S. apiospermum endophthalmitis treated with intravitreal and systemic voriconazole.

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A pseudophakic patient presented with a vitreous haemorrhage and iris neovascularization associated with proliferative diabetic retinopathy. Vitrectomy with panretinal photocoagulation and intraocular gas tamponade of an iatrogenic break was performed. As an alternative to intravitreal injection into a gas-filled eye, triamcinolone acetonide was injected into the anterior chamber.

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Purpose: To describe corneal perforation secondary to severe peripheral ulcerative keratitis (PUK) in a patient with Crohn disease.

Methods: Interventional case report.

Results: A 72-year-old male with biopsy-proven Crohn disease presented with reduced vision, PUK, and corneal perforation in the right eye.

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Purpose: To evaluate the safety and efficacy of intravitreal triamcinolone acetonide (IVTA) for ischemic macular edema associated with branch retinal vein occlusion (BRVO) and foveal ischemia.

Design: Prospective interventional case series.

Methods: setting: Clinical practice.

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Malignant glaucoma is a rare secondary glaucoma classically occurring after intraocular surgery in eyes with primary angle closure. Pars plana vitrectomy is reserved for the treatment of malignant glaucoma when medical and laser treatment fail. The primary aim of surgery is the removal of the anterior vitreous to reduce resistance to aqueous flow into the anterior chamber.

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Purpose: To describe a method that permits optical coherence tomography scanning to be performed under general anesthesia.

Design: Observational case report.

Methods: A 7-year-old child underwent optical coherence tomography scanning under general anesthesia.

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