Publications by authors named "Simon Couly"

Synopsis of recent research by authors named "Simon Couly"

  • Simon Couly's research focuses on the sigma-1 receptor (S1R) and its crucial role in neuroprotection and cellular health, particularly in the context of neurodegenerative diseases like Alzheimer's, Huntington's, and Wolfram syndrome.
  • His studies reveal that S1R acts as a chaperone protein that modulates mitochondrial function and calcium signaling, influencing both cell survival and physiological brain plasticity.
  • Recent findings demonstrate the therapeutic potential of targeting S1R to alleviate symptoms of neurodegenerative conditions and enhance resilience against cellular stress, underscoring its significance as a genetic modulator in diseases like amyotrophic lateral sclerosis (ALS).