Publications by authors named "Simon Braak"
Article Synopsis
- Social dysfunction is a common feature of neuropsychiatric disorders like Schizophrenia and Alzheimer's disease, impacting socioaffective neural processing.
- A study analyzed how social dysfunction correlates with brain system activity in SZ and AD patients through fMRI tasks, revealing patterns related to emotional responses.
- The research found that severe behavioral social dysfunction linked to hyperactivity and hypoactivity in specific brain regions, highlighting the potential for tailored care based on individual social behavior.
The pursuit for markers of disease progression in behavioral variant frontotemporal dementia: a scoping review to optimize outcome measures for clinical trials.
Jay L P Fieldhouse Dirk N van Paassen Marie-Paule E van Engelen Sterre C M De Boer Willem L Hartog Simon Braak
Front Aging Neurosci
May 2024
Behavioral variant frontotemporal dementia (bvFTD) is a neurodegenerative disorder characterized by diverse and prominent changes in behavior and personality. One of the greatest challenges in bvFTD is to capture, measure and predict its disease progression, due to clinical, pathological and genetic heterogeneity. Availability of reliable outcome measures is pivotal for future clinical trials and disease monitoring.
View Article and Find Full Text PDF