Role of corticosteroids in Functional Endoscopic Sinus Surgery--a systematic review and meta-analysis.

Background: The aim of our study is to systematically review the existing evidence on the role of corticosteroids in patients undergoing functional endoscopic sinus surgery (FESS).

Methodology: Systematic search of MEDLINE (1950- 2014), EMBASE (1980-2014), metaRegister, Cochrane Library and ISI conference proceedings was carried out.

Results: Eighteen randomised controlled trials with 1309 patients were included.

A case of bilateral sensorineural hearing loss from Langerhans cell histiocytosis.

Langerhans cell histiocytosis is a rare disorder, with resultant bilateral sensorineural hearing loss unreported in adults. A 42-year-old man presented with 4 months of right-sided tinnitus and hearing loss treated initially as otitis media with effusion. He re-presented 5 months later with progressive bilateral hearing loss--sensorineural (>100 dB) on pure tone audiogram.

A rare case of breast cancer metastasising to the nasopharynx and paranasal sinuses.

Introduction: Metastatic spread from non-head and neck tumours to the sinonasal region is exceedingly rare. We present a case of breast cancer metastasis to the nasopharynx, ethmoid and sphenoid sinuses. To date there have been only two similar cases in the literature.

Occult renal cell carcinoma manifesting with epistaxis in a woman: a case report.

Introduction: Metastatic disease in the sinonasal region occurs rarely and the primary site may be elusive. This case highlights the possibility of an occult renal tumor manifesting with nasal symptoms and the risk of severe bleeding following nasal biopsy.

Case Presentation: We report the case of a 79-year-old Caucasian woman who presented with a six-week history of intermittent left-sided nosebleeds.