A Resident-Led Quality Improvement Initiative to Increase End-of-Life Planning in Primary Care.

Despite many benefits of end-of-life (EOL) planning, only 1 in 3 adults has EOL documentation, with low rates in resident primary care clinics as well. To increase clinic completion of life-sustaining treatment (LST) notes and advance directives (AD) for veterans at highest risk for death. The setting was a Veterans Affairs (VA) internal medicine primary care clinic.

Ursodeoxycholic acid versus phenobarbital for cholestasis in the Neonatal Intensive Care Unit.

Background: Although neonates and young infants with cholestasis are commonly treated with either phenobarbital or ursodeoxycholic acid (ursodiol), there is no evidence that phenobarbital is effective for this indication. Our objective was to compare the effectiveness of ursodiol and phenobarbital for the treatment of cholestasis in a diverse NICU population.

Methods: This is a retrospective cohort study including infants with cholestasis who were admitted to a Level IV NICU between January 2010 and December 2015.