Publications by authors named "Simeon J Ortega Lozano"
Background: Multiple system atrophy (MSA) is a neurodegenerative disease. It has a fast progression, so early diagnosis is decisive. Two functional imaging tests can be involved in its diagnosis: [I]Ioflupane SPECT and [I]MIBG scintigraphy.
View Article and Find Full Text PDFBackground: Multiple system atrophy (MSA) is subdivided into two types: MSA-P (parkinsonian) and MSA-C (cerebellar). Brain SPECT allows for the detection of nigrostriatal involvement, even in the early stages. To date, the scientific literature does not show a consensus on how to follow-up MSA, especially MSA-C.
View Article and Find Full Text PDFArticle Synopsis
- Multiple system atrophy (MSA) is a serious neurodegenerative disorder with no cure, and its diagnosis follows specific criteria.
- A study involving 139 patients at the initial suspicion of MSA found that [I]Ioflupane SPECT is effective, revealing positive results in 78.45% of cases, especially strong in MSA-P subtypes.
- The findings suggest that [I]Ioflupane SPECT is a reliable diagnostic tool that significantly differentiates between healthy individuals and those with MSA, as well as between the different subtypes of the disease.
Background And Objective: To assess the functional state of nigro-striatal pathway using FP-CIT-I-123 in patients with clinical diagnosis of Multiple System Atrophy (MSA) subtype C.
Patients And Methods: We included 10 patients with a clinical diagnosis of MSA-C and compared them with 10 patients diagnosed with essential tremor (controls) and 10 with Parkinson Disease (PD). The studies are evaluated by the striatum/occipital index (S/O).
Objective: To compare various published thallium-201 uptake indexes in the differential diagnosis in recurrent brain gliomas.
Material And Methods: Thallium-201 SPECT studies were performed in 79 patients previously treated for glial tumor with clinical or radiologic suspicion of recurrence. Regions of interest were established in the tumor area and in other sites with normal uptake.