Efficacy and Mechanism of Core Traditional Chinese Medicines for Treating Malignant Lymphoma based on Efficacy Studies: A Study Supported by Network Pharmacology and Molecular Docking.

Background: The burden of malignant lymphoma in China is greater than the global equivalent. The randomized controlled trials provide medical evidence that TCM can improve the response and survival in patients with lymphoma. However, the mechanisms underlying remain undefined.

Compound Kushen Injection Reduces Severe Toxicity and Symptom Burden Associated With Curative Radiotherapy in Patients With Lung Cancer.

Background: Radiotherapy (RT) causes adverse events for which there are no effective treatments. This study investigated the clinical benefits of compound Kushen injection (CKI) in managing radiation injury in patients with lung cancer.

Methods: A multicenter, open-label, randomized clinical trial randomly assigned patients with lung cancer to receive either CKI (20 mL/d for at least 4 weeks) integrated with curative RT (RT + CKI group; n=130) or RT alone (control group; n=130).

6,12-Dihydro-6,12-diboradibenzo[def,mno]chrysene: A Doubly Boron-Doped Polycyclic Aromatic Hydrocarbon for Organic Light Emitting Diodes by a One-Pot Synthesis.

One-pot synthesis of a new doubly boron-doped polycyclic aromatic hydrocarbon of 6,12-dimesityl-6,12-dihydro-6,12-diboradibenzo[def,mno]chrysene (MDBDBC) was reported. MDBDBC features a rigid planar electron-deficient core structure and demonstrates good chemical and thermal stabilities. A low-lying LUMO of -3.