Cerebrovascular mechanical properties and slow waves of intracranial pressure in TBI patients.

Myogenic autoregulation of cerebral blood flow is one of the mechanisms affecting cerebral hemodynamics. Short or long-lasting changes in intracranial pressure (ICP) are believed to reveal the responses of the cerebral system to myogenic stimuli. Through the incorporation of a theoretical model into the experimental measurements of cerebrovascular distensibility and compliance in patients with traumatic brain injury (TBI), the current study is an attempt to explain ICP dynamics in either presence or absence of cerebral autoregulation.

Frequency interpretation of tidal peak in intracranial pressure wave.

A new approach to locate different components of ICP signal for each cardiac induced ICP beat is presented. In this method an initial timing map is used to define the appropriate part of the ICP wave which should be searched for the specific component. In parallel a recently proposed method was used to decompose the ICP wave to its different frequency harmonics.

Harmonics tracking of intracranial and arterial blood pressure waves.

Considering cardiorespiratory interaction and heart rate variability, a new approach is proposed to decompose intracranial pressure and arterial blood pressure to their different harmonics. The method is based on tracking the amplitudes of the harmonics by a Kalman filter based tracking algorithm. The algorithm takes benefit of combined frequency estimation technique which uses both Fast Fourier Transform and RR-interval detection.

A comparison between the transfer function of ABP to ICP and compensatory reserve index in TBI.

Background: The transfer functions which map the arterial blood pressure to the intracranial pressure and the compensatory reserve index have been investigated by various groups to evaluate the brain compliance of patients with traumatic brain injury. The focus of this study has been to assess the capability of both the above mentioned methods to monitor the intracranial compliance in patients suffering from brain swelling.

Materials And Methods: Clinical data was collected from sixteen traumatic brain injury patients and split into 4 min segments.