Publications by authors named "Sima Sadray"

Article Synopsis
  • The study investigates how different bleaching methods (conventional and laser-assisted) affect the release of specific monomers from two types of composite materials used in dental applications.
  • Results showed that nanohybrid composites released more monomers, particularly BIS-GMA, compared to microhybrid composites, with significant differences observed in the laser-assisted bleaching group.
  • Conclusions indicate that using laser-assisted bleaching with JW Power gel results in higher monomer release from nanohybrid composites, potentially affecting their structural properties.
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The potential for continuous infusion of cimetidine to affect the clearance of aminophylline was assessed in 18 critically ill patients treated for bronchospasm. This was a pharmacokinetic drug-drug interaction study in which the subjects were administered aminophylline as a continuous infusion at low doses (mean 10.8 mg/hr).

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Generalized least squares regression with variance function estimation was used to derive the calibration function for measurement of methotrexate plasma concentration and its results were compared with weighted least squares regression by usual weight factors and also with that of ordinary least squares method. In the calibration curve range of 0.05 to 100 microM, both heteroscedasticity and non-linearity were present therefore ordinary least squares linear regression methods could result in large errors in the calculation of methotrexate concentration.

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