Supravalvular and valvular aortic stenosis in heterozygous familial hypercholesterolemia.

Objectives: To report calcified aortic stenosis due to hypercholesterolemia in two siblings.

Case Presentation And Intervention: A 13-year-old boy with a history of dyspnea on exertion and a systolic murmur of aortic stenosis was referred to our center. Echocardiography showed combined valvular and supravalvular aortic stenoses with a good left ventricle systolic function and severe left ventricular hypertrophy.

Pulse tissue Doppler analysis of tricuspid annular motion in Iranian children.

Background: Quantitative assessment of right ventricular (RV) function has been difficult to assess non-invasively secondary to its non-geometric shape and respiratory-variable filling. With recent improvements in ultrasound equipment we are now able to study myocardial velocity changes, which is known as tissue Doppler imaging.

Objectives: To define normal indices of tricuspid pulse tissue Doppler echocardiography imaging in children and infants.