Evaluating the Toxocara cati extract as a therapeutic agent for allergic airway inflammation.

Background: The hygiene hypothesis suggests that early life exposure to helminth infections can reduce hypersensitivity in the immune system.

Objective: The present study aims to evaluate the effects of Toxocara cati (T. cati) somatic products on allergic airway inflammation.

Exacerbation of allergic asthma by somatic antigen of Echinococcus granulosus in allergic airway inflammation in BALB/c mice.

Background: There is ample evidence demonstrating a reverse relationship between helminth infection and immune-mediated diseases. Accordingly, several studies have shown that Echinococcus granulosus infection and hydatid cyst compounds are able to suppress immune responses in allergic airway inflammation. Previous studies have documented the ability of hydatid cysts to suppress aberrant Th2 immune response in a mouse model of allergic asthma.

Evaluation of the effect of Toxocara cati infection in the mouse model of allergic asthma: Exacerbation of allergic asthma symptoms and Th2 types of response.

Toxocariasis is considered a neglected disease despite the importance of Toxocara spp. infections for human health and is little recognized as a significant problem by public health institutions in developing countries. Epidemiological studies suggest that infection with Toxocara cati contributes to the development of allergic asthma.

A survey on Toxocara cati eggs on the hair of stray cats: A potential risk factor for human toxocariasis in Northeastern Iran.

The objective of this study was to investigate the presence of Toxocara eggs on the hair of stray cats. The total number of stray cats trapped and included in the trial was 167 that were collected weekly from different residential areas of Mashhad, in northeastern Iran, from November 2016 to December 2017. Among the 167 cats, 18 (10.

Molecular Characterization of Sensu Lato from Livestock in North Khorasan Province, Iran.

Background: is one the most important zoonotic disease which is endemic in worldwide. Molecular method has allowed discrimination of different genotypes (G1-G10), providing new approach in development of prevention and control program of hydatid cyst. This study was conducted to identify the genotypes of from domestic animals in nine districts of North Khorasan Province using the mitochondrial cox1 gene sequence.

Somatic extracts of Marshallagia marshalli downregulate the Th2 associated immune responses in ovalbumin-induced airway inflammation in BALB/c mice.

Background: Recently the role of gastrointestinal nematodes in modulating the immune responses in inflammatory and immune-mediated conditions such as allergy and autoimmune diseases has been introduced. This is mainly due to the suppressive effects of somatic and excretory secretory (ES) products of nematodes on the immune responses. In this study, we evaluated the immunomodulatory potentials of somatic products of Marshallagia marshalli, a gastrointestinal nematodes of sheep, to suppress the immune-mediated responses in a murine model of allergic airway inflammation.

Anti-inflammatory Potentials of Excretory/Secretory (ES) and Somatic Products of on Allergic Airway Inflammation in BALB/c Mice.

Background: Inverse relationship between helminths infection and immune-mediated diseases has inspired researchers to investigate therapeutic potential of helminths in allergic asthma. Helminth unique ability to induce immunoregulatory responses has already been documented in several experimental studies. This study was designed to investigate whether excretory/secretory (ES) and somatic products of modulate the development of ovalbumin-induced airway inflammation in a mouse model.