Publications by authors named "Silvio Henrique De Freitas"

The dorsal and ventral nasal conchal bullae and conchal sinuses are part of the complex equine paranasal sinus system and are commonly affected by secondary sinusitis. However, the radiographic anatomy of the conchal sinuses is poorly reported in the literature. The present study aimed to describe the radiographic anatomical characteristics of the nasal conchal bullae and conchal sinuses in mature horses.

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Article Synopsis
  • The maxillary septum and septal bullae in horses can complicate the interpretation of radiographs, making it hard to diagnose sinus disorders due to their anatomical variations.
  • This study utilized six preserved equine cadaver heads to detail the anatomical and radiographic features of these structures, highlighting that their positioning can differ between specimens and sides.
  • Specific radiographic techniques, particularly oblique offset positioning, were found effective in visualizing the maxillary septum and bullae, which have normal variations in size and location within the equine species.
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Background: Preservation of biological tissues has been used since ancient times. Regardless of the method employed, tissue preservation is thought to be a vital step in veterinary surgery teaching and learning.

Objectives: This study was designed to determine the usability of chemically preserved cadaveric equine heads for surgical teaching in veterinary medicine.

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Article Synopsis
  • * A new study developed a co-culture system with neoplastic mast cells and cancer-associated fibroblasts to better understand these cells' properties and behaviors.
  • * Results showed that mast cells survive better with direct cell-to-cell contact, particularly in high-grade tumours, suggesting that the communication between these cells could be potential targets for treating MCT progression.
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Background: For horses requiring prolonged daily cephalic intravenous regional limb perfusion (IVRLP), the use of a totally implantable catheter (TIC) could be indicated to reduce complications associated with frequent venipuncture or external catheterization. This study aims to evaluate the implantation technique of the TIC in the cephalic vein of horses for IVRLP, describe the complications associated with the device's placement and use, and assess its viability up to 60 days after implantation. Totally implantable catheters, cut to 15 cm (n = 5) and 46 cm (n = 5) in length, were implanted into one cephalic vein in ten adult horses (n = 10).

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The use of live animals for educational purposes is an old practice that is still employed in teaching and research institutions. However, there are several objections to this practice, whether for ethical or humanitarian reasons. Surgical techniques teaching using anatomical pieces and/or preserved cadavers promotes greater learning efficiency, provides exercise repetition and increases the confidence and satisfaction of the students when compared to the use of live animals.

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Purpose: To analyze and compare the reactions at the interface between the composite, composed of fragmented heterologous mineralized bone matrix (MOMHF) and polymethylmethacrylate (PMMA), and the rabbit's tibias, through macroscopic evaluation and scanning electron microscopy (SEM) in different periods.

Methods: In this study, 12 New Zealand adult rabbits were used (E1: n = 3, E2: n = 3, E3: n = 3 and E4: n = 3). They had the right tibial defects filled with composite and were evaluated immediately after surgery and at 30, 60, 90, and 120 days.

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Mast cell tumours (MCTs) are common neoplasms in dogs and are usually regarded as potentially malignant. Several studies have attempted to identify biomarkers to better predict biological behaviours for this tumour. The aim of this study was to identify pathways connected to clinical and histopathological malignancies, shorter survival times, and poor prognoses associated with MCTs.

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Purpose: To evaluate abdominal ventral wound healing by using a specific biomaterial, a handmade polyamide surgical mesh.

Methods: A surgical incisional defect was made in ten rabbits to simulate a hernia in the ventral abdominal musculature. A polyamide surgical mesh was used in hernioplasty.

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Purpose: To evaluate the performance of composites consisting of fragmented cortical bone heteroimplant in association with methylmethacrylate preserved in 98% glycerin, in segmental bone defect of rabbit tibia medial metaphysis.

Methods: In this study were used twelve adult New Zealand rabbits, divided into three groups of four animals each: G30 (30 days), G60 (60 days) and G90 (90 days). The bone defects previously created in the tibia were filled with composites and both were evaluated by cone-beam computed tomography, immediately after surgery and after 30, 60, and 90 days.

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