Publications by authors named "Silvienne C Sint Jago"
Article Synopsis
- Ageing is a growing global concern, with projections that by 2030, one in six people will be 60 or older, highlighting the need to understand the biological processes and healthcare challenges associated with ageing.
- The World Health Organization defines intrinsic capacity (IC) as the collective physical and mental abilities of an individual, with five vital components: locomotion, cognition, psychological, sensory, and vitality capacity (VC).
- The review emphasizes the benefits of exercise in maintaining VC among older adults, discussing its positive effects on energy metabolism, neuromuscular function, immune response, mitochondrial health, and gene methylation, while also identifying potential areas for future research and interventions.
The therapeutic potential of aerobic exercise in mitigating seizures and cognitive issues in temporal lobe epilepsy (TLE) is recognized, yet the underlying mechanisms are not well understood. Using a rodent TLE model induced by Kainic acid (KA), we investigated the impact of a single bout of exercise (i.e.
View Article and Find Full Text PDFDysregulation of long non-coding RNAs (lncRNAs) have been associated with Alzheimer's disease (AD). However, the functional role of lncRNAs in AD remains unclear. Here, we report a crucial role for the lncRNA in astrocyte dysfunction and memory deficits associated with AD.
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