Publications by authors named "Silvia Wallisch"

Correction for 'A library of action spectra for erythema and pigmentation' by Alois W. Schmalwieser et al., Photochem.

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Mutations in sunlight-induced melanoma arise from cyclobutane pyrimidine dimers (CPDs), DNA photoproducts that are typically created picoseconds after an ultraviolet (UV) photon is absorbed at thymine or cytosine. We found that in melanocytes, CPDs are generated for >3 hours after exposure to UVA, a major component of the radiation in sunlight and in tanning beds. These "dark CPDs" constitute the majority of CPDs and include the cytosine-containing CPDs that initiate UV-signature C→T mutations.

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The first action spectra for erythema and delayed pigmentation in human skin were determined 90 years ago by Karl Hausser and Wilhelm Vahle in Germany, and since then a number of studies have been undertaken to redefine these action spectra. In this paper we give an overview of the action spectra for erythema and pigmentation that have been published during this 90-yr period, as well as indicating their uncertainties and shortcomings.

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In this study the personal exposure to solar UV radiation in an urban environment was measured. Lifestyle in an urban environment is characterized by staying indoors during most of the day. Furthermore, the ambient UV radiation is mitigated by shadowing by buildings.

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