Sequential Custom Therapeutic Keratectomy for the Treatment of Granular Corneal Dystrophy Type 1: A Long-term Study.

Purpose: To evaluate the effectiveness of sequential custom phototherapeutic keratectomy (SCTK) for granular corneal dystrophy type 1 (GCD1).

Methods: Thirty-seven eyes of 21 patients with GCD1 were treated with SCTK to remove superficial opacifications, regularize the corneal surface, and decrease optical aberrations. SCTK is a sequence of custom therapeutic excimer laser keratectomies with step-by-step intraoperative corneal topography monitoring of results.

Corneal Apical Scar After Hyperopic Excimer Laser Refractive Surgery: Long-term Follow-up of Treatment With Sequential Customized Therapeutic Keratectomy.

Purpose: To evaluate long-term results of sequential customized therapeutic keratectomy (SCTK) in highly aberrated corneas with apical scars consequent to hyperopic excimer laser refractive surgery.

Methods: Fifteen eyes of 12 patients treated with SCTK for a corneal apical scar after hyperopic excimer laser refractive surgery were retrospectively evaluated. SCTK is a sequence of custom therapeutic excimer laser keratectomies where the results are monitored step-by-step by intraoperative corneal topography.

Long-term resolution of immunological graft rejection after a dexamethasone intravitreal implant.

Purpose: To present the results of the injection of an intravitreal implant of dexamethasone 0.7 mg (DEX 0.7 mg) in 4 patients with an immunologic graft rejection after penetrating keratoplasty.

Corneal curvature gradient map: a new corneal topography map to predict the corneal healing process.

Purpose: To evaluate a new curvature gradient topography map to predict postoperative corneal remodeling.

Methods: In this retrospective study, 32 eyes of 16 patients with myopia underwent excimer ablation surgery with a postoperative high curvature gradient. The new curvature gradient map (acquired immediately postoperatively) shows the difference between the curvatures of two points over the distance between them; it was compared to the tangential curvature difference map between 1 and 12 months postoperatively to determine their relationship.

Corneal cross-linking as a treatment for keratoconus: four-year morphologic and clinical outcomes with respect to patient age.

Purpose: To report the 4-year outcomes of corneal cross-linking (CXL) for progressive keratoconus in a population of different age groups.

Design: Retrospective, single-center, nonrandomized clinical study.

Participants: Four hundred consecutive eyes treated with corneal CXL for progressive keratoconus from April 2006 through April 2010.

Two-year corneal cross-linking results in patients younger than 18 years with documented progressive keratoconus.

Purpose: To report refractive, topographic, aberrometric, and tomographic outcomes 24 months after corneal cross-linking (CXL) in patients up to 18 years of age with progressive keratoconus.

Design: Prospective, interventional case series.

Methods: Forty eyes underwent riboflavin-ultraviolet A-induced CXL.

Intra- and postoperative variation in ocular response analyzer parameters in keratoconic eyes after corneal cross-linking.

Purpose: To analyze intra- and postoperative variation in Ocular Response Analyzer (ORA, Reichert Ophthalmic Instruments) parameters in 24 keratoconic eyes undergoing corneal cross-linking (CXL).

Methods: In a prospective clinical study, corneal hysteresis (CH), corneal resistance factor (CRF), peak 1 and peak 2 amplitude, corneal-compensated and Goldmann-correlated intraocular pressure (IOP) were evaluated using the ORA. The thinnest cornea point was measured with the Pentacam (Oculus Inc).

Intraoperative and postoperative effects of corneal collagen cross-linking on progressive keratoconus.

Objectives: To report intraoperative and 24-month refractive, topographic, tomographic, and aberrometric outcomes after corneal collagen cross-linking in progressive advanced keratoconus.

Methods: Prospective, nonrandomized single-center clinical study involving 28 eyes. Main outcome measures included uncorrected and best spectacle-corrected visual acuities, sphere and cylinder refraction, topography, tomography, aberrometry, and endothelial cell count evaluated at baseline and follow-up at 1, 3, 6, 12, and 24 months after treatment.

Corneal collagen cross-linking for ectasia after excimer laser refractive surgery: 1-year results.

Purpose: To evaluate the 1-year results of corneal collagen cross-linking (CXL) in eyes with postoperative excimer laser refractive surgery corneal ectasia.

Methods: Thirteen eyes of 9 consecutive patients who had undergone excimer laser refractive surgery (photorefractive keratectomy [n = 3], LASIK [n = 10]) with resultant unstable corneal ectasia underwent CXL with photosensitizing riboflavin 0.1% solution and subsequent exposure to ultraviolet radiation.

Photorefractive keratectomy for primary myopia using NIDEK topography-guided customized aspheric transition zone.

Purpose: To report the outcomes of topography-guided photorefractive keratectomy (PRK) for the treatment of myopia with or without astigmatism using the customized aspheric transition zone (CATz) ablation algorithm.

Methods: In this study, 335 eyes underwent PRK using the NIDEK Advanced Vision Excimer laser platform (NAVEX). Mean preoperative manifest refraction spherical equivalent was -4.

Refractive, topographic, tomographic, and aberrometric analysis of keratoconic eyes undergoing corneal cross-linking.

Purpose: To report refractive, topographic, tomographic, and aberrometric outcomes 12 months after corneal cross-linking (CXL) in eyes with progressive advanced keratoconus.

Design: Prospective, nonrandomized, single-center clinical study.

Participants: Twenty-eight eyes undergoing CXL between April and June 2006.

Wavefront- versus topography-guided customized ablations with the NIDEK EC-5000 CX II in surface ablation treatment: refractive and aberrometric outcomes.

Purpose: To compare the long-term refractive outcomes and changes in higher order wavefront aberrations in patients undergoing photorefractive keratectomy (PRK) with topography-guided (CATz) or wavefront-guided (OPDCAT) ablation algorithm using the NIDEK Advanced Vision Excimer Laser System (NAVEX).

Methods: A retrospective 12-month follow-up study was conducted of 226 eyes undergoing PRK. The NIDEK EC-5000 CX II excimer laser and Final Fit 1.