Oral infections and orofacial pain in Alzheimer's disease: a case-control study.

Background: Dental infections are frequent and have recently been implicated as a possible risk factor for Alzheimer's disease (AD). Despite a lack of studies investigating orofacial pain in this patient group, dental conditions are known to be a potential cause of pain and to affect quality of life and disease progression.

Objectives: To evaluate oral status, mandibular function and orofacial pain in patients with mild AD versus healthy subjects matched for age and gender.

Orofacial pain and sensory characteristics of chronic patients compared with controls.

Objectives: To investigate orofacial and sensorial characteristics of patients with orofacial pain and healthy controls.

Study Design: Case-control. Seventy-five patients (61 women) who had chronic orofacial pain for more than 6 months (i.

Oral infections and orofacial pain in Alzheimer's disease: Case report and review.

Dental infections, frequent in the general population, are a common cause of inflammation with systemic impact, and are the most common cause of orofacial pain. Temporomandibular disorders are also frequent in the elderly and represent an important cause of secondary headache. Both inflammation and pain can also contribute to cognitive, functional and behavioral impairment of the elderly and aggravate symptoms of patients with Alzheimer's disease (AD).