Open-label topical application of tetrahexyldecyl ascorbate and acetyl zingerone containing serum improves the appearance of photoaging and uneven pigmentation.

Background: Skin photoaging and uneven pigmentation are common dermatological concerns. Tetrahexyldecyl ascorbate (THDA) and acetyl zingerone (AZ) are potent antioxidants that have been shown to have anti-photoaging and anti-pigmentation effects. THDA is a more stable and penetrable form of vitamin C.

Comparison between HET-CAM protocols and a product use clinical study for eye irritation evaluation of personal care products including cosmetics according to their surfactant composition.

The hen's egg test on chorioallantoic membrane (HET-CAM) is one of the most frequently used alternative tests for prediction of ocular irritation of cosmetic products. There are different HET-CAM protocols widely accepted, but there is no information about which of the protocols better correlates with the results obtained in product use clinical study under the conditions of use. Two Fix Time Methods (FTM) -Lüepke and the ICCVAM guideline - and two Reaction Time Methods (RTM) -ECVAM DBALM Prot.

Jarilla-Coffea extract: a natural cosmetic product that improves eyelash and eyebrow growth in women.

Purpose: A combination of extracts, from two plant species, ie, and (Jarilla) (ECOHAIR) is being successfully used in Argentina as a cosmetic for hair recovery in androgenic and areata alopecia, and for eyelash and eyebrow growth. The objectives of this prospective study were to evaluate the capacity of Jarilla-Coffea extract gel of improving hair growth in relation to thickness, appearance of new hair, and hair length in comparison with a placebo in premenopausal and postmenopausal volunteers and to identify possible signs of ocular adverse local reactions related to the application of the gel.

Volunteers And Methods: An open-label, placebo-controlled, prospective study was performed in healthy premenopausal and postmenopausal women during a daily administration period of 2 months (eyebrow growth) and 3 months (eyelash growth).

Freshness evaluation of refreshing creams: influence of two types of peppermint oil and emulsion formulation.

The aim of the present work was to study the influence of emulsion composition and two types of peppermint oil (common and dementholated) on freshness perception (skin feel) of refreshing creams, as evaluated by trained assessors and two consumer panels. Both common peppermint oil (PO) and dementholated peppermint oil (DPO) were added in a 1% concentration to two base emulsions formulated with high (emulsion A) and low (emulsion B) concentration of apolar components. The samples' freshness was evaluated by a panel of trained assessors and by consumers.