Publications by authors named "Silvia Perez Esteban"
Article Synopsis
- This study investigates the risk factors for severe COVID-19 in patients with immune-mediated rheumatic diseases, focusing on different types of autoimmune conditions and chronic arthritis.
- Conducted as a multicenter observational study in Madrid, it involved 523 patients diagnosed with severe COVID-19, analyzing their outcomes based on various demographic and clinical factors.
- Key findings revealed that male gender, older age, and certain comorbidities, along with specific medications like corticosteroids and rituximab, were linked to worse COVID-19 outcomes, while treatments like methotrexate showed no negative impact.
Introduction: Rheumatoid arthritis (RA) is a complex polygenic inflammatory disease associated with accelerated atherosclerosis. IL-6 is a key mediator of inflammation in RA. A recent study showed an association between IL6-174 G/C gene polymorphism and cardiovascular (CV) disease in UK individuals with RA.
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