Publications by authors named "Silvia Marcos de Pedro"
The concept of the brain has shifted to a complex system where different subnetworks support the human cognitive functions. Neurodegenerative diseases would affect the interactions among these subnetworks and, the evolution of impairment and the subnetworks involved would be unique for each neurodegenerative disease. In this study, we seek for structural connectivity traits associated with the family history of Alzheimer's disease, that is, early signs of subnetworks impairment due to Alzheimer's disease.
View Article and Find Full Text PDFAge and APOE genotype affect the relationship between objectively measured physical activity and power in the alpha band, a marker of brain disease.
Jaisalmer de Frutos-Lucas Pablo Cuesta Federico Ramírez-Toraño Alberto Nebreda Esther Cuadrado-Soto Silvia Marcos-de Pedro
Alzheimers Res Ther
September 2020
Article Synopsis
- - Research shows that physical activity (PA) may help protect against Alzheimer’s disease (AD) by increasing alpha brain wave power, which is often reduced in AD.
- - A study of 113 healthy adults found that while younger adults showed a clear positive relationship between PA and alpha power, this was only partially observed in older adults with different genetic risks (APOE ε3 and ε4 carriers).
- - The findings suggest that engaging in physical activity may help maintain brain function and structure, particularly in older adults who carry the higher risk APOE ε4 gene.