Publications by authors named "Silvia K Kavaguti"
Article Synopsis
- After surviving sepsis, adults often have weakened immune systems and more chances of getting sick again, but it's unclear how this happens in kids.
- The study looked at different aged mice (2-week-old vs 6-week-old) to see how their immune systems responded after sepsis and found that younger mice were better at fighting off infections.
- The research suggests that older mice had higher levels of a substance called IL-33, which affects immune cells, while younger mice's immune systems reacted differently, showing that age impacts how sepsis affects patients.
Background: Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs in pediatric sepsis is unknown.
Methods: Infant (2 weeks old) and adult (6 weeks old) mice were submitted to sepsis by intraperitoneal (i.
The authors report a case of abdominal compartment syndrome caused by massive pyonephrosis in an infant with primary obstructive megaureter successfully treated with emergency surgical decompression.
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