Publications by authors named "Silvia Garcia-Vilana"

Traumatic brain injuries (TBI) resulting from head impacts are a major public health concern, which prompted our research to investigate the complex relationship between the material properties of brain tissue and the severity of TBI. The goal of this research is to investigate how variations in brain and skull density influence the vulnerability of brain tissue to traumatic injury, thereby enhancing our understanding of injury mechanism. To achieve this goal, we employed a well-validated finite element head model (FEHM).

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Article Synopsis
  • The study investigates the relationship between CPR practices and ribcage injuries, identifying key risk factors contributing to severe damage during resuscitation.
  • Data were gathered from 200 out-of-hospital CPR attempts, revealing that a significant 65% of patients suffered serious ribcage injuries, with age and cardiac mass ratio as major influencing factors.
  • The findings suggest that understanding the heart's role in CPR biomechanics is crucial, highlighting the importance of cardiac mass ratio as a significant risk factor for injuries during CPR.
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The objective of this study was to quantitatively investigate the relationship between cerebral atrophy and the risk of injury in elderly individuals. To achieve this, a sophisticated computational biomechanics approach utilizing finite element analysis was employed to simulate the mechanical behavior of the brain and skull under various conditions. In addition, particular emphasis was placed on understanding the role of cerebral bridging veins (BVs) and their mechanical properties at different ages in the occurrence of head injuries.

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. We aim to characterize the viscoelastic behavior of Polyether-Block-Amide (PEBA 90A), provide reference values for the parameters of a constitutive model for the simulation of mechanical behaviors, and paying attention to the influence of the manufacturing conditions. .

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Aim: To determine compression force variation (CFV) during mechanical cardiopulmonary resuscitation (CPR) and its relationship with CPR-related injuries and survival.

Methods: Adult non-traumatic OHCA patients who had been treated with mechanical CPR were evaluated for CPR-related injuries using chest X-rays, thoracic computed tomography or autopsy. The CFV exerted by the LUCAS 2 device was calculated as the difference between the maximum and the minimum force values and was categorised into three different groups (high positive CFV ≥ 95 newton (N), high negative CFV ≤ -95 N, and low variation for intermediate CFV).

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Worldwide, the ocurrence of acute subdural hematomas (ASDHs) in road traffic crashes is a major public health problem. ASDHs are usually produced by loss of structural integrity of one of the cerebral bridging veins (CBVs) linking the parasagittal sinus to the brain. Therefore, to assess the risk of ASDH it is important to know the mechanical conditions to which the CBVs are subjected during a potentially traumatic event (such as a traffic accident or a fall from height).

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Many previous studies on the mechanical properties of Parasagittal Bridging Veins (PSBVs) found that strain rate had a significant effect on some mechanical properties, but did not extensively study the viscoelastic effects, which are difficult to detect with uniaxial simple tensile tests. In this study, relaxation tests and tests under cyclic loading were performed, and it was found that PSBVs do indeed exhibit clear viscoelastic effects. In addition, a complete viscoelastic model for the PSBVs is proposed and data from relaxation, cyclic load and load-unload tests for triangular loads are used to find reference values that characterize the viscoelastic behavior of the PSBVs.

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Article Synopsis
  • Researchers investigated the mechanical properties of cerebral bridging veins (CBVs) using advanced microtensile tests, revealing a nonlinear stress-strain response and viscoelastic behavior under cyclic loading.
  • * Previous studies utilizing uniaxial tensile tests overlooked these viscoelastic effects, but the more sensitive methods used in this research allowed for their observation.
  • * The study also includes a mathematical analysis explaining why previous tests didn't detect viscoelasticity and provides reference values and constitutive parameters for more accurate numerical simulations in future computational models.
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Purpose: The aim of this paper is to propose a fracture model for human ribs based on acoustic emission (AE) data. The accumulation of microcracking until a macroscopic crack is produced can be monitored by AE. The macrocrack propagation causes the loss of the structural integrity of the rib.

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  • A study analyzed the mechanical properties of ribs from 64 human subjects of varying ages, sexes, and BMI to understand how these factors impact rib strength and flexibility.
  • The researchers performed uniaxial tensile tests on rib bone samples, measuring properties like yield stress, ultimate stress, and resilience, aiming to isolate mechanical characteristics from shape influences.
  • Results indicated that age significantly affects rib properties, with older age linked to lower failure stress and ultimate strain, and higher BMI further reduces strain in older individuals.
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A large number of post mortem human subjects was used to investigate the relation between the micro-structure of rib cortical bone and the mechanical properties using Fractal Dimension. Uniaxial tensile tests were performed on coupons of rib cortical bone. Tensile strength, yield stress, Young's Modulus, maximum strain, and work to fracture were determined for each coupon.

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